Exercise-induced proteinuria in diabetic children

Simpson, L. O.

doi:10.1007/bf01271178

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Proteinuria In Diabetes1

Insulin Does Not Aggregate Its Own Receptor1

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1983

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“…We would like to make a few comments of a technical nature concerning the statements in the letter by Dr. Simpson in the August 1982 issue [1]. When assessing proteinuria as a marker of glomerular function, it is essential to quantitate specifically and accurately one or more proteins, the renal handling characteristics of which are known and understood.…”

Section: Proteinuria In Diabetesmentioning

confidence: 99%

“…The concept that insulin can aggregate its own receptor is used by Jeffrey [1] to formulate a hypothesis of the mechanism of insulin action. However, experiments [2] using insulin labelled with ferritin as an ultrastructural marker for the insulin receptor, do not support the idea of hormone-induced receptor aggregation.…”

Section: Insulin Does Not Aggregate Its Own Receptormentioning

confidence: 99%

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