Exercise Program for Nursing Home Residents with Alzheimer's Disease: A 1‐Year Randomized, Controlled Trial

Rolland, Yves; Pillard, Fabien; Klapouszczak, Adrian; Reynish, Emma; Thomas, David; Andrieu, Sandrine; Rivière, D.; Vellas, Bruno

doi:10.1111/j.1532-5415.2007.01035.x

Cited by 570 publications

(645 citation statements)

References 40 publications

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“…Fifteen papers, relating to 13 randomised controlled trials met our inclusion criteria (Table 1) (Tappen et al, 2000;Cott et al, 2002;Baum et al, 2003; Teri et al, 2003;Toulotte et al, 2003;Van de Winckel et al, 2004;Littbrand et al, 2006;Rosendahl et al, 2006;Netz et al, 2007;Rolland et al, 2007;Burgener et al, 2008;Kwak et al, 2008;Santana-Sosa et al, 2008;Tappen, 2007, 2008). Most trials were small, the 13 trials included a total of 896 participants, (range 16-191 participants), and six trials had less than 20 participants in the intervention group.…”

Section: Outcome Of the Search Strategymentioning

confidence: 99%

“…Most trials were small, the 13 trials included a total of 896 participants, (range 16-191 participants), and six trials had less than 20 participants in the intervention group. Only five of the 15 papers included any power calculations for their primary outcomes (Cott et al, 2002;Baum et al, 2003;Teri et al, 2003;Rosendahl et al, 2006;Rolland et al, 2007). All reported calculations based on 80% power with an a of 0.05 with the exception of Cott et al, who expected a large effect size and set a at 0.01.…”

Section: Outcome Of the Search Strategymentioning

confidence: 99%

“…There were also five trials from Europe (Toulotte et al, 2003;Van de Winckel et al, 2004;Rosendahl et al, 2006;Rolland et al, 2007;Santana-Sosa et al, 2008) and one each from Korea (Kwak et al, 2008) and Israel (Netz et al, 2007). Eight of the trials were conducted in the institutions in which the patients were resident which were variously described as care homes, institutions or hospitals (Tappen et al, 2000;Cott et al, 2002;Baum et al, 2003;Toulotte et al, 2003;Van de Winckel et al, 2004;Rolland et al, 2007;Williams and Tappen, 2007;Santana-Sosa et al, 2008). The other interventions were either delivered in a community facility (Netz et al, 2007;Burgener et al, 2008;Kwak et al, 2008), in the patient's home (Teri et al, 2003) or in a sheltered housing complex .…”

Section: Outcome Of the Search Strategymentioning

confidence: 99%

“…The level of cognition of participants varied from a mean MMSE score of 6 (AE6) (Cott et al, 2002) to 24.8 (AE 3.5) (Burgener et al, 2008). Dementia was formally diagnosed in eight of the studies (Tappen et al, 2000;Cott et al, 2002;Teri et al, 2003;Van de Winckel et al, 2004;Rolland et al, 2007;Williams and Tappen, 2007;Burgener et al, 2008;Santana-Sosa et al, 2008).…”

Section: Outcome Of the Search Strategymentioning

confidence: 99%

“…A Cochrane systematic review (Forbes et al, 2008) found insufficient evidence to determine whether physical activity programmes were beneficial for people with dementia. However, the review included only one trial reporting the effect of physical activity on depression, which showed a non-significant improvement in depression at both 6 and 12 months (Rolland et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

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A systematic review of the effects of physical activity on physical functioning, quality of life and depression in older people with dementia

Potter

Ellard

Rees

et al. 2011

Int J Geriat Psychiatry

173

131

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Background: Depression is common in older people with dementia. Physical activity is effective in reducing depression in adults but there is limited evidence about its effectiveness in people with dementia. Design and Methods: A systematic review and partial meta-analysis of physical activity interventions in people with dementia is reported. We searched eight databases for English language papers and reference lists of relevant papers. Included studies reported a physical activity intervention lasting at least 12 weeks in which participants were older and had a diagnosis of dementia. Studies compared the intervention with a non-active or a no-intervention control and reported at least one outcome related to physical function, quality of life or depression. At least two authors independently assessed each paper for inclusion and for study quality and extracted data. Results: We included 13 randomised controlled trials with 896 participants. Three of six trials that reported walking as an outcome found an improvement, as did four of the five trials reporting timed get up and go tests. Only one of the four trials that reported depression as an outcome found a positive effect. Both trials that reported quality of life found an improvement. Conclusions: There is some evidence that physical activity interventions improve physical function in older people with dementia. Evidence for an effect on depression and quality of life is limited.

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Section: Outcome Of the Search Strategymentioning

confidence: 99%

Section: Outcome Of the Search Strategymentioning

confidence: 99%

Section: Outcome Of the Search Strategymentioning

confidence: 99%

Section: Outcome Of the Search Strategymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A systematic review of the effects of physical activity on physical functioning, quality of life and depression in older people with dementia

Potter

Ellard

Rees

et al. 2011

Int J Geriat Psychiatry

173

131

View full text Add to dashboard Cite

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Effects of Exercise Programs to Prevent Decline in Health-Related Quality of Life in Highly Deconditioned Institutionalized Elderly Persons

Dechamps¹

2010

Arch Intern Med

134

151

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Effects of the Finnish Alzheimer Disease Exercise Trial (FINALEX)

Pitkälä¹,

Pöysti²,

Laakkonen³

et al. 2013

JAMA Intern Med

267

375

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Few rigorous clinical trials have investigated the effectiveness of exercise on the physical functioning of patients with Alzheimer disease (AD). Objectives: To investigate the effects of intense and longterm exercise on the physical functioning and mobility of home-dwelling patients with AD and to explore its effects on the use and costs of health and social services. Design: A randomized controlled trial. Setting and Participants: A total of 210 homedwelling patients with AD living with their spousal caregiver. Interventions: The 3 trial arms included (1) groupbased exercise (GE; 4-hour sessions with approximately 1-hour training) and (2) tailored home-based exercise (HE; 1-hour training), both twice a week for 1 year, and (3) a control group (CG) receiving the usual community care. Main Outcome Measures: The Functional Independence Measure (FIM), the Short Physical Performance Battery, and information on the use and costs of social and health care services. Results: All groups deteriorated in functioning during the year after randomization, but deterioration was significantly faster in the CG than in the HE or GE group at 6 (P=.003) and 12 (P=.015) months. The FIM changes at 12 months were Ϫ7.1 (95% CI, Ϫ3.7 to Ϫ10.5), Ϫ10.3 (95% CI, Ϫ6.7 to Ϫ13.9), and Ϫ14.4 (95% CI, Ϫ10.9 to Ϫ18.0) in the HE group, GE group, and CG, respectively. The HE and GE groups had significantly fewer falls than the CG during the follow-up year. The total costs of health and social services for the HE patient-caregiver dyads (in US dollars per dyad per year) were $25

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Exercise Program for Nursing Home Residents with Alzheimer's Disease: A 1‐Year Randomized, Controlled Trial

Abstract: A simple exercise program, 1 hour twice a week, led to significantly slower decline in ADL score in patients with AD living in a nursing home than routine medical care.

Cited by 570 publications

References 40 publications

A systematic review of the effects of physical activity on physical functioning, quality of life and depression in older people with dementia

A systematic review of the effects of physical activity on physical functioning, quality of life and depression in older people with dementia

Effects of Exercise Programs to Prevent Decline in Health-Related Quality of Life in Highly Deconditioned Institutionalized Elderly Persons

Effects of the Finnish Alzheimer Disease Exercise Trial (FINALEX)

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