Exercise response in tetralogy of Fallot and pulmonary atresia with ventricular septal defect

Paridon, Stephen M.

doi:10.1016/1058-9813(93)90054-4

Cited by 5 publications

(7 citation statements)

References 31 publications

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“…The maximal VO 2 in both groups of our study are similar to values reported in previous studies of patients with TOF, summarized in a review of exercise performance following repair of TOF by Paridon [5]. This finding indicates that the presence of a transannular patch does not result in a lower aerobic capacity than in those repaired without such a patch.…”

Section: Cardiovascular Factors Affecting Aerobic Performancesupporting

confidence: 92%

“…This finding indicates that the presence of a transannular patch does not result in a lower aerobic capacity than in those repaired without such a patch. It is a somewhat surprising finding, as pulmonary regurgitation was thought to correlate with decreased aerobic capacity in many previous studies and all of the patients in our current study have unrestricted pulmonary regurgitation [1,5,9,16,17].…”

Section: Cardiovascular Factors Affecting Aerobic Performancementioning

confidence: 73%

“…Several previous studies suggested that chronotropic impairment is a significant factor in determining aerobic capacity following repair of TOF [4,5,7,12]. These studies again suffer from the heterogeneity of their patient population.…”

Section: Cardiovascular Factors Affecting Aerobic Performancementioning

confidence: 95%

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Determinants of Aerobic Capacity During Exercise Following Complete Repair of Tetralogy of Fallot with a Transannular Patch

et al. 1997

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Exercise capacity and the causes of its limitation following repair of tetralogy of Fallot have been studied in heterogeneous populations. Study populations have been grouped together regardless of the type of repair and residual hemodynamic abnormalities. To better understand the factors limiting aerobic exercise capacity in patients repaired with a transannular patch, 37 patients with a transannular patch and no residual pulmonary stenosis underwent resting spirometry and treadmill exercise testing. Maximal oxygen consumption and oxygen consumption at anaerobic threshold were measured in all patients to assess aerobic capacity. Patients were subdivided by gender. Resting spirometry measurements tended to be lower in both genders compared to healthy controls but did not correlate with any measurement of aerobic capacity. Maximal oxygen consumption and anaerobic threshold were significantly less in the female than the male population. A quadratic relation between maximal oxygen consumption and age at exercise testing existed for both genders but peaked at an earlier age and was significantly less in the female population. There was a significant negative correlation between maximal oxygen consumption and echocardiographically estimated right ventricular inflow volume index in the female population only. These data suggest that in patients with tetralogy of Fallot repaired with a transannular patch aerobic capacity is limited primarily by cardiac function, but that gender differences are due to noncardiac causes.

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Section: Cardiovascular Factors Affecting Aerobic Performancesupporting

confidence: 92%

Section: Cardiovascular Factors Affecting Aerobic Performancementioning

confidence: 73%

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Determinants of Aerobic Capacity During Exercise Following Complete Repair of Tetralogy of Fallot with a Transannular Patch

et al. 1997

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“…It is nevertheless important to measure aerobic capacity in this group, as it may prove useful in the functional assessment of the surgical repair or palliation, particularly when compared to patients who have similar congenital defects. Values for aerobic capacity are available for most large groups of patients with different structural defects [23][24][25][26][27][28][29][30]. These values are frequently more useful in assessing the success of a palliation in a complex defect, such as functionally univentricular physiology, than exercise data from healthy control populations.…”

Section: Aerobic Capacitymentioning

confidence: 98%

“…Measurements of pulmonary function with exercise are often abnormal in children with structural heart defects [28,29,31,32]. The causes of these abnormalities are not entirely clear, but are probably multifactorial.…”

Section: Pulmonary Function During Exercisementioning

confidence: 99%

Interaction of the Heart and Lungs During Exercise: Physiology and Pathophysiology in Children with Congenital Heart Disease

McBride¹,

Brothers²,

Stephens³

et al. 2011

CRMR

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The modern era of surgical palliation, perioperative strategies, and myocardial preservation has dramatically altered the long-term outcome for children with congenital heart disease. Even children surgically corrected for more complex heart disease are now surviving to ages where physical activity and sports participation are not only considered but encouraged by pediatric cardiologists secondary to the benefits of regular physical activity on cardiovascular risk factors. In this review, basic cardiovascular and pulmonary responses to exercise performance are reviewed. In addition, the interaction of the cardiovascular and pulmonary systems during exercise in children with simple and complex congenital heart disease is reviewed.

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Exercise Physiology and Capacity

Paridon

2003

Developments in Cardiovascular Medicine

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Exercise response in tetralogy of Fallot and pulmonary atresia with ventricular septal defect

Cited by 5 publications

References 31 publications

Determinants of Aerobic Capacity During Exercise Following Complete Repair of Tetralogy of Fallot with a Transannular Patch

Determinants of Aerobic Capacity During Exercise Following Complete Repair of Tetralogy of Fallot with a Transannular Patch

Interaction of the Heart and Lungs During Exercise: Physiology and Pathophysiology in Children with Congenital Heart Disease

Exercise Physiology and Capacity

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