“…It is also doubtful whether persons with back pain develop aerobic deconditioning or whether reduced aerobic fitness is associated with other aspects related to CBP such as pain intensity, activity limitation, depression, fear of injury and kinesiophobia [7,15,26,37,38,42,43]. Furthermore, there is inconclusive evidence for the predictive value of aerobic fitness for work-return in CBP [20,22,24,33] Although in general aerobic fitness shows a doseresponse relation to health outcomes [3], at present, there is modest evidence to suggest that exercise therapy and behavioural and multidisciplinary treatment programs that include exercise therapy are effective in reducing pain, improving physical functioning and activity and reducing the number of sick days in CBP [6,19,23,27,34]. Depending on intensity and duration, many of these programs for persons with CBP that include aerobic training do indeed affect aerobic fitness [28,33,36].…”