Exercise Training and Cardiac Rehabilitation in Primary and Secondary Prevention of Coronary Heart Disease

Lavie, Carl J.; Thomas, Randal J.; Squires, Ray W.; Allison, Thomas G.; Milani, Richard V.

doi:10.1016/s0025-6196(11)60548-x

Cited by 241 publications

(120 citation statements)

References 105 publications

Supporting

Mentioning

107

Contrasting

Unclassified

Order By: Relevance

“…We also found that men with higher CRF levels had higher survival rates when compared with unfit men and that abnormal E-ECG test results were associated with an increased risk of all-cause mortality. 4,25,26 Our current results further strengthen the prognostic power of E-ECG testing in men with MetS.…”

Section: Discussionsupporting

confidence: 70%

Maximal Exercise Electrocardiographic Responses and Coronary Heart Disease Mortality Among Men With Metabolic Syndrome

Lyerly

Sui²,

Church

et al. 2010

Mayo Clinic Proceedings

Self Cite

View full text Add to dashboard Cite

Objective: To examine the association between abnormal exercise electrocardiographic (E-ECG) test results and mortality (all-cause and that resulting from coronary heart disease [CHD] or cardiovascular disease [CVD]) in a large population of asymptomatic men with metabolic syndrome (MetS).patients and MethOds: A total of 9191 men (mean age, 46.9 years) met the criteria of having MetS. All completed a maximal E-ECG treadmill test (May 14, 1979, through April 9, 2001) and were without a previous CVD event or diabetes at baseline. Main outcomes were all-cause mortality, mortality due to CHD, and mortality due to CVD. Cox regression analysis was used to quantify the mortality risk according to E-ECG responses.Results: During a follow-up of 14 years, 633 deaths (242 CVD and 150 CHD) were identified. Mortality rates and hazard ratios (HRs) across E-ECG responses were the following: for all-cause mortality: HR, 1.36; 95% confidence interval (CI), 1.09-1.70 for equivocal responses and HR, 1.41; 95% CI, 1.12-1.77 for abnormal responses (P trend <.001); for mortality due to CVD: HR, 1.29; 95% CI, 0.88-1.88 for equivocal responses and HR, 2.04; 95% CI, 1.46-2.84 for abnormal responses (P trend <.001); and for mortality due to CHD: HR, 1.62; 95% CI, 1.02-2.56 for equivocal responses and HR, 2.45; 95% CI, 1.62-3.69 for abnormal responses (P trend <.001). A positive gradient for CHD, CVD, and all-cause mortality rates across E-ECG categories within 3, 4, or 5 MetS components was observed (P<.001 for all).cOnclusiOn: Among men with MetS, an abnormal E-ECG response was associated with higher risk of all-cause, CVD, and CHD mortality. These findings underscore the importance of E-ECG tests to identify men with MetS who are at risk of dying. Proc. 2010;85(3):239-246 ACLS = Aerobics Center Longitudinal Study; CHD = coronary heart disease; CI = confidence interval; CRF = cardiorespiratory fitness; CVD = cardiovascular disease; DM = diabetes mellitus; ECG = electrocardiography; E-ECG = exercise ECG; HR = hazard ratio; MET = metabolic equivalent; MetS = metabolic syndrome; NDI = National Death Index; SRI = stress-recovery index From the department of Kinesiology, school of health, Kinesiology, and sport studies, coastal carolina university, conway, sc (G.W.l.); department of exercise science (G.W.l., X.s., G.a.h., s.n.b.) and department of epidemiology and biostatistics (s.n.b.), arnold school of public health, university of south carolina, columbia; pennington biomedical Research center, baton Rouge, la (t.s.c.); and department of cardiovascular diseases, Ochsner Medical center, new Orleans, la (c.j.l.). the aerobics center longitudinal study was supported by national institutes of health grants aG06945 and hl62508. Mayo Clinindividual reprints of this article are not available. address correspondence to G. William lyerly, phd, department of Kinesiology, school of health, Kinesiology, and sport studies, coastal carolina university, pO box 261954, conway, sc 29528 (glyerly@coastal.edu). © 2010 Mayo Foundation for Medical Education ...

show abstract

Section: Discussionsupporting

confidence: 70%

Maximal Exercise Electrocardiographic Responses and Coronary Heart Disease Mortality Among Men With Metabolic Syndrome

Lyerly

Sui²,

Church

et al. 2010

Mayo Clinic Proceedings

Self Cite

View full text Add to dashboard Cite

show abstract

“…Research evidence indicates that physical activity declines with age, with the steepest decline occurring between the ages of 13 and 18 (J. F. Sallis, 2000). Reduced physical activity levels in children and adolescents may affect health negatively, and inactivity may increase risks of developing health threatening conditions such as obesity (González-Gross & Meléndez, 2013) and coronary heart disease (Lavie, Thomas, Squires, Allison, & Milani, 2009) among other.…”

Section: Introductionmentioning

confidence: 99%

Untitled

Erdvik¹,

Øverby²,

Haugen³

2014

JPES

View full text Add to dashboard Cite

Abstract:Purpose: This study examined whether high school students' degree of self-determined motivation in school physical education predicted their intentions to be physically active after graduation, and whether perceived physical competence and physical activity identity mediated this hypothesized cross-sectional relationship. Additionally, the possibility of conditional effects of gender on these associations was considered. Method: A cross sectional study involving 1650 high-school students allowed for the examination of indirect effects using a bias-corrected bootstrapping technique. Results: Results showed that self-determination in PE may positively affect adolescents' intentions to be physically active after graduation, both independently and through the strengthening of students' physical activity identity and perceived physical competence. Moderation analysis identified that the indirect effect of perceived competence on the adolescents' physical activity intentions was only significant in boys. Identity however, was a significant mediator of physical activity intention in both genders. Conclusions: School interventions aiming to improve adolescents' physical activity intentions might take advantage of increasing adolescents' physical activity identities as well as perceived physical competence.

show abstract

“…Furthermore, based on many clinical and experimental studies, it is evident that exercise training is a very potent tool in secondary prevention (reviewed in Ref. 45). A primary target of the exercise intervention seems to be the impaired endothelial function (20,65).…”

mentioning

confidence: 99%

Role of endothelial progenitor cells in the beneficial effects of physical exercise on atherosclerosis and coronary artery disease

Lenk

Uhlemann

Schuler

et al. 2011

Journal of Applied Physiology

View full text Add to dashboard Cite

show abstract

Exercise Training and Cardiac Rehabilitation in Primary and Secondary Prevention of Coronary Heart Disease

Cited by 241 publications

References 105 publications

Maximal Exercise Electrocardiographic Responses and Coronary Heart Disease Mortality Among Men With Metabolic Syndrome

Maximal Exercise Electrocardiographic Responses and Coronary Heart Disease Mortality Among Men With Metabolic Syndrome

Untitled

Role of endothelial progenitor cells in the beneficial effects of physical exercise on atherosclerosis and coronary artery disease

Contact Info

Product

Resources

About