“…The performance bias risk was unclear for six studies (29,32,33,35,38,39), and it was low risk for four trials (1,30,31,37). The risk of detection bias was low risk in six of the twelve studies (30,31,34,35,37,38); unclear in four trials 1,23,27,33 , and high in two study (32,36). Attrition bias was low in six trials (31)(32)(33)(34)(35)39), unclear in four trials (1,29,30,38), and high in two (36,37).…”