This paper reports on a study of the modelling, validation and analysis of an integrated 1 MW (electrical output) tri-generation system energized by solar energy. The impact of local climatic conditions in the Mediterranean region on the system performance was considered. The output of the system that comprised a parabolic trough collector (PTC), an organic Rankine cycle (ORC), single-effect desalination (SED), and single effect LiBr-H2O absorption chiller (ACH) was electrical power, distilled water, and refrigerant load. The electrical power was produced by the ORC which used cyclopentane as working fluid and Therminol VP-1 was specified as the heat transfer oil (HTO) in the collectors with thermal storage. The absorption chiller and the desalination unit were utilize the waste heat exiting from the steam turbine in the ORC to provide the necessary cooling energy and drinking water respectively. The modelling, which includes an exergetic analysis, focuses on the performance of the solar tri-generation system. The simulation results of the tri-generation system and its subsystems were produced using IPSEpro software and were validated against experimental data which showed good agreement. The tri-generation system was able to produce about 194 Ton of refrigeration, and 234 t/day distilled water.