2016
DOI: 10.4168/aair.2015.8.1.12
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Exhaled NO: Determinants and Clinical Application in Children With Allergic Airway Disease

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Cited by 5 publications
(5 citation statements)
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“…Determinants of exhaled NO includes age, sex, body height, atopy and smoking status, but in our study exhaled NO correlates only with age, and in spite of a significant correlation, it is weak and was not possible to derive any equation of reference values (results not shown). In developing individuals, exhaled NO increases until 14 years in females and 16 in males, and similar development is observed for anatomic dead space volume .…”
Section: Discussioncontrasting
confidence: 59%
See 1 more Smart Citation
“…Determinants of exhaled NO includes age, sex, body height, atopy and smoking status, but in our study exhaled NO correlates only with age, and in spite of a significant correlation, it is weak and was not possible to derive any equation of reference values (results not shown). In developing individuals, exhaled NO increases until 14 years in females and 16 in males, and similar development is observed for anatomic dead space volume .…”
Section: Discussioncontrasting
confidence: 59%
“…First, the large number of asthmatic children in our study being treated with inhaled corticosteroids, a well‐known modifier of exhaled NO levels and a high prevalence of allergic rhinitis, which is usually correlated with exhaled NO levels. Secondly, our evaluations were conducted during pollen season, contributing to high exhaled NO levels, even when asthma was not present, in pollen allergic patients . Thirdly, the use of respiratory symptoms with high levels of exhaled NO as a definition of uncontrolled asthma, and the subsequent evaluation of an association with exhaled NO ratio may lead to a risk of circular reasoning.…”
Section: Discussionmentioning
confidence: 99%
“…It was reported that diffusing capacity of NO in the bronchial wall of patients with AR was high, suggesting subclinical change of bronchial mucosa in AR [17]. The nasal nitric oxide levels were found to decrease in children with AR after topical corticosteroids were administered [18].…”
Section: Discussionmentioning
confidence: 91%
“…17,18 Furthermore, a previous study found that perennial allergic rhinitis was associated with high FeNO levels and more severe asthma. Those patients in the FeNO high group reported that their symptoms were more likely to be induced by allergen exposure.…”
Section: Discussionmentioning
confidence: 99%