This paper deals with the existence and global exponential stability of almost periodic solutions for quaternion‐valued high‐order Hopfield neural networks with delays by a direct approach. Based on the contraction mapping principle, sufficient conditions are derived to ensure the existence and uniqueness of almost periodic solutions for the networks under consideration. By constructing a suitable Lyapunov function, the global exponential stability criterion of the almost periodic solution are derived. Finally, two numerical examples are given to illustrate the main results of this paper.