This paper considers the existence and multiplicity of fixed points for the integral operatorwhere λ > 0 is a positive parameter, k : I × I → R is a kernel function such that k ∈ W m,1 (I × I), m is a positive integer with m ≥ 1, and f :The existence of solutions for these Hammerstein equations is obtained by fixed point index theory on new type of cones. Therefore some assumptions must hold only for, at least, one of the derivatives of the kernel or, even, for the kernel, on a subset of the domain. Assuming some asymptotic conditions on the nonlinearity f , we get sufficient conditions for multiplicity of solutions.Two examples will illustrate the potentialities of the main results, namely the fact that the kernel function and/or some derivatives may only be positive on some subintervals, which can degenerate to a point. Moreover, an application of our method to general Lidstone problems improves the existent results on the literature in this field.