The basic necessary conditions for the existence of a (v, k, λ)-perfect Mendelsohn design (briefly (v, k, λ)-PMD) are v ≥ k and λv(v − 1) ≡ 0 (mod k). These conditions are known to be sufficient in most cases, but certainly not in all. For k = 3, 4, 5, 7, very extensive investigations of (v, k, λ)-PMDs have resulted in some fairly conclusive results. However, for k = 6 the results have been far from conclusive, especially for the case of λ = 1, which was given some attention in papers by Miao and Zhu [34], and subsequently by Abel et al. [1]. Here we investigate the situation for k = 6 and λ > 1. We find that the necessary conditions, namely v ≥ 6 and λv(v − 1) ≡ 0 (mod 6) are sufficient except for the known impossible cases v = 6 and either λ = 2 or λ odd.Keywords Perfect Mendelsohn design · Incomplete Perfect Mendelsohn design · Holey Perfect Mendelsohn design · GDD · PBD