Exoftalmos unilateral como debut de mieloma múltiple no secretor

Castro-Rebollo, M.; Cañones-Zafra, Rafael; Vleming-Pinilla, Eduardo; Drake-Rodríguez-Casanova, P; Pérez-Rico, C.

doi:10.4321/s0365-66912009001200008

Cited by 4 publications

(1 citation statement)

References 6 publications

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“…Multiple Myeloma (MM) is a monoclonal proliferation of plasma cell that causes destructive skeletal lesions and secondary systemic effects, and is a systemic disease diagnosed in the presence of light chain (Bence Jones) proteinuria, lytic skeletal lesions, and characteristic pathology. It accounts for about 10% of the hematological malignancies, with an incidence of 5.5 cases per 100,000 inhabitants [1]. The median age at diagnosis is 70 years and only 3.4% of cases are diagnosed between 35 -44 years of age [2].…”

Section: Introductionmentioning

confidence: 99%

Orbital Involvement in Multiple Myeloma: A Case Report

Terenzi¹,

Cristino²,

Murgia³

et al. 2012

JCT

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Purpose: To report a retro-orbital localization of Multiple Myeloma (MM) describing its treatment and clinical result. Case report: A 50-years-old male patient with Magnetic Resonance Imaging (MRI) evidence of a retro-orbital mass with exophthalmos, due to the pathological diagnosis of MM, was referred for Radiation Therapy (RT). Discussion: The orbital involvement in Multiple Myeloma is rare and few cases are reported in the literature. The treatment of choice is RT alone with a prescribed dose ranging between 40 Gy and 45 Gy. In our patient the retro-orbital lesion, measuring 26 × 16 mm, was treated with Intensity Modulated Radiotherapy Technique (IMRT) delivering 4400 cGy with conventional fractionation. The treatment was well tolerated, the patient experienced a complete regression of the exophthalmos without any significant side effect

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Section: Introductionmentioning

confidence: 99%