Exogenous lipoid pneumonia

Kennedy, JD; Costello, Philip; Balikian, JP; Pg, Herman

doi:10.2214/ajr.136.6.1145

Cited by 68 publications

(34 citation statements)

References 11 publications

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“…At a later stage, fibrotic proliferation can result in decreased lung volume. (4) Most of the oil coalesces, forming large fat drops surrounded by fibrous tissue and giant cells, creating a tumor mass known as paraffinoma. (10) Repeated massive aspiration results in diffuse parenchymal consolidation, similar to that found in lobar pneumonia.…”

Section: Discussionmentioning

confidence: 99%

“…Severe destruction of the lung architecture can lead to terminal lung disease or cor pulmonale. (4) The clinical profile of lipoid pneumonia is nonspecific and depends on the length of exposure and the quantity of oil that has been aspirated or inhaled. Patients can be asymptomatic or can present with dyspnea, with or without chronic productive cough.…”

Section: Discussionmentioning

confidence: 99%

“…(3) Chronic lipoid pneumonia has been found to develop after the prolonged use of mineral oil-as an oral laxative (for constipation) or as nasal drops (for chronic rhinitis)-animal oils, such as cod liver oil (as a dietary supplement for children)-or vegetable oils, such as sesame oil (for balancing cholesterol levels). (4) In contrast, acute chronic pneumonia results from massive accidental aspiration of lipid material, as can occur in "fire eaters". (5) There are, however, other types of oil that are used therapeutically and can, therefore, cause lipoid pneumonia.…”

Section: Introductionmentioning

confidence: 99%

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Pneumonia lipoide secundária ao uso prolongado de óleo de prímula

et al. 2010

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A 50-year-old never-smoking female, born and raised in the city of Goiânia, Brazil, presented with a two-year history of productive cough. She had no other complaints. The only finding during the physical examination was scattered fine rales on pulmonary auscultation.After the initial investigation, the patient was diagnosed with bronchial hyperresponsiveness associated with gastroesophageal reflux IntroductionMicroaspiration of lipid substances can lead to lipoid pneumonia.(1) The reported cases have been associated with the therapeutic use of mineral oil as a laxative by individuals with chronic constipation. However, other forms of treatment with lipid preparations might be implicated. We report the case of a female patient with chronic exogenous lipoid pneumonia secondary to the use of evening primrose oil. AbstractLipoid pneumonia is an underdiagnosed disease that is caused by the aspiration of lipid particles into the lungs. Although most of the reported cases have been associated with the use of mineral oil as a laxative, other lipid substances can also cause the disease. We report the case of a 50-year-old female patient with a complaint of productive cough who was initially diagnosed with bronchial hyperresponsiveness and gastroesophageal reflux disease (GERD). The patient was treated for GERD. Because the productive cough persisted, the patient underwent chest CT, fiberoptic bronchoscopy, and open lung biopsy. She was diagnosed with lipoid pneumonia. The patient was questioned regarding the use of lipid substances, and she reported the chronic use of evening primrose oil. After the discontinuation of the substance and the maintenance of GERD treatment, her condition improved.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pneumonia lipoide secundária ao uso prolongado de óleo de prímula

et al. 2010

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“…The presumptive diagnosis can be made based on a history of use of oils, either as nose drops or feeding, in the infant. The diagnosis is confirmed by the presence of lipid-laden macrophages in sputum or material obtained from bronchoalveolar lavage, 10 or from histological examination of specimens obtained from transbronchial biopsy, 17 percutaneous fine needle aspirate of the lung, 18 or open lung biopsy. Because of the implication that lipoid pneumonia may induce bronchogenic carcinoma, particularly the alveolar cell or squamous cell type, 19,21 and biopsy specimen obtained at surgery showed complete obliteration of the normal lung architecture, we elected to do serial segmental/ lobar resections to remove as much of the involved granulomatous lung as possible.…”

Section: Discussionmentioning

confidence: 99%

Infantile Lipoid Pneumonia

et al. 1990

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“…[29] Involvement may be diffuse or focal, unilateral or bilateral, although unilateral pneumonic consolidation with lower lobes predilection is more commonly reported. [29,30,32,33] Occasionally, one may also LIPOID PNEUMONIA Þ nd cavitation. [34,35] A reticular pattern may be observed as the emulsiÞ ed oil leaves the alveoli and enters the interstitium and lymphatics, creating edema, inß ammation, and Þ brosis in those sites.…”

Section: Radiological Featuresmentioning

confidence: 99%