Exogenous Melatonin Improves Plant Iron Deficiency Tolerance via Increased Accumulation of Polyamine-Mediated Nitric Oxide

Zhou, Cheng; Zhi, Liu; Zhu, Lin; Ma, Zhongyou; Wang, Jianfei; Zhu, Jian Kang

doi:10.3390/ijms17111777

Cited by 88 publications

(48 citation statements)

References 56 publications

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“…It was observed that NO serves as a modulator of MEL accretion during the distal signaling response. Similarly, studies of Zhou et al showcased the interdependency between MEL and NO during iron (Fe) deficiency in Arabidopsis plants. In this study, it was observed that Fe deficiency quickly induced MEL biosynthesis.…”

Section: Mel‐mediated Stress Ameliorationmentioning

confidence: 88%

“…Therefore, it was proposed that NO plays a key role in polyamine‐mediated signaling pathways. On similar lines, Zhou et al provided concrete evidence documenting that exogenous applied MEL improves plant Fe deficiency tolerance in Arabidopsis plants via increasing polyamine‐mediated NO production. MEL was shown to induce PA metabolism in cucumber plants while conferring chilling tolerance with the co‐participation of ABA via modulating the transcripts of genes regulating ABA metabolism .…”

Section: Mel‐mediated Stress Ameliorationmentioning

confidence: 92%

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Phytomelatonin: Recent advances and future prospects

Kanwar

Zhou

2018

Journal of Pineal Research

175

109

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Melatonin (MEL) has been revealed as a phylogenetically conserved molecule with a ubiquitous distribution from primitive photosynthetic bacteria to higher plants, including algae and fungi. Since MEL is implicated in numerous plant developmental processes and stress responses, the exploration of its functions in plant has become a rapidly progressing field with the new paradigm of involvement in plants growth and development. The pleiotropic involvement of MEL in regulating the transcripts of numerous genes confirms its vital involvement as a multi‐regulatory molecule that architects many aspects of plant development. However, the cumulative research in plants is still preliminary and fragmentary in terms of its established functions compared to what is known about MEL physiology in animals. This supports the need for a comprehensive review that summarizes the new aspects pertaining to its functional role in photosynthesis, phytohormonal interactions under stress, cellular redox signaling, along with other regulatory roles in plant immunity, phytoremediation, and plant microbial interactions. The present review covers the latest advances on the mechanistic roles of phytomelatonin. While phytomelatonin is a sovereign plant growth regulator that can interact with the functions of other plant growth regulators or hormones, its qualifications as a complete phytohormone are still to be established. This review also showcases the yet to be identified potentials of phytomelatonin that will surely encourage the plant scientists to uncover new functional aspects of phytomelatonin in plant growth and development, subsequently improving its status as a potential new phytohormone.

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Section: Mel‐mediated Stress Ameliorationmentioning

confidence: 88%

Section: Mel‐mediated Stress Ameliorationmentioning

confidence: 92%

Phytomelatonin: Recent advances and future prospects

Kanwar

Zhou

2018

Journal of Pineal Research

175

109

View full text Add to dashboard Cite

show abstract

“…The NO signal up-regulates the expression of iron-related genes such as FIT1, FRO2, and IRT1, thereby inducing the reactivation of iron in the cell wall, and increased availability of soluble iron. These phenomena were completely suppressed in the polyamine-and NO-deficient plants [38]. The NO-melatonin crosstalk is therefore partially related to the polyamine-mediated signaling pathway.…”

Section: Regulatory Roles Of Melatonin and Nitric Oxide In Plant Growmentioning

confidence: 87%

“…Iron deficiency often causes chlorosis and inhibits normal plant growth [114]. The application of exogenous polyamines causes an increase in NO production, indicating that NO is a key intermediate in the polyamine-mediated signaling pathway [38]. NO can increase the soluble iron content, and ameliorate leaf chlorosis and oxidative stress.…”

Section: Regulatory Roles Of Melatonin and Nitric Oxide In Plant Growmentioning

confidence: 99%

Melatonin-Nitric Oxide Crosstalk and Their Roles in the Redox Network in Plants

Zhu

Gao

Lü

et al. 2019

IJMS

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Melatonin, an amine hormone highly conserved during evolution, has a wide range of physiological functions in animals and plants. It is involved in plant growth, development, maturation, and aging, and also helps ameliorate various types of abiotic and biotic stresses, including salt, drought, heavy metals, and pathogens. Melatonin-related growth and defense responses of plants are complex, and involve many signaling molecules. Among these, the most important one is nitric oxide (NO), a freely diffusing amphiphilic biomolecule that can easily cross the cell membrane, produce rapid signal responses, and participate in a wide variety of physiological reactions. NO-induced S-nitrosylation is also involved in plant defense responses. NO interacts with melatonin as a long-range signaling molecule, and helps regulate plant growth and maintain oxidative homeostasis. Exposure of plants to abiotic stresses causes the increase of endogenous melatonin levels, with the consequent up-regulation of melatonin synthesis genes, and further increase of melatonin content. The application of exogenous melatonin causes an increase in endogenous NO and up-regulation of defense-related transcription factors, resulting in enhanced stress resistance. When plants are infected by pathogenic bacteria, NO acts as a downstream signal to lead to increased melatonin levels, which in turn induces the mitogen-activated protein kinase (MAPK) cascade and associated defense responses. The application of exogenous melatonin can also promote sugar and glycerol production, leading to increased levels of salicylic acid and NO. Melatonin and NO in plants can function cooperatively to promote lateral root growth, delay aging, and ameliorate iron deficiency. Further studies are needed to clarify certain aspects of the melatonin/NO relationship in plant physiology.

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“…Furthermore, Fe deficiency quickly induced melatonin biosynthesis in Arabidopsis plants, acting synergistically with exogenous treatments. In mutant plants deficient in polyamine and nitric oxide (NO) biosynthesis, the protective role of melatonin was not observed, indicating that the process is dependent on the polyamine induced NO production under Fe deficient conditions [84]. In a similar work, tomato seedlings grown in an S deficient medium suffered serious growth inhibition as a result of a reduced chlorophyll content, photosynthesis, and biomass accumulation; it also led to cell structural alterations and DNA damage.…”

Section: Metals As a Severe Abiotic Stress And Effects Induced By Melmentioning

confidence: 98%

Role of Melatonin to Enhance Phytoremediation Capacity

Arnao

Hernández‐Ruíz

2019

Applied Sciences

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Phytoremediation is a green technology that aims to take up pollutants from soil or water. Metals are one of the targets of these techniques due to their high toxicity in biological systems, including plants and animals. Their elimination or, at least, decrease will help keep them from being incorporated in the trophic chain and thus reaching animal and human food. The metal removal efficiency of plants is closely related to their growth rate, tolerance, and their adaptability to different environments. Melatonin (N-acetyl-5-methoxytryptamine) is a ubiquitous molecule present in animals, plants, fungi, and bacteria. In plants, it plays an important role related to antioxidant activity, but also as an important redox network regulator. Thus, melatonin has been defined as a biostimulator of plant growth, especially under environmental stress conditions, whether abiotic (water deficit and waterlogging, extreme temperature, UV radiation, salinity, alkalinity, specific mineral deficit/excess, metals and other toxic compounds, etc.) or biotic (bacteria, fungi, and viruses). Exogenous melatonin treated plants have been seen to have a high tolerance to stressors, minimizing possible harmful effects through the control of reactive oxygen species (ROS) levels and activating antioxidative responses. Furthermore, important gene expression changes in stress specific transcription factors have been demonstrated. Melatonin is capable of mobilizing toxic metals, through phytochelatins, transporting this, while sequestration adds to the biostimulator effect of melatonin on plants, improving plant tolerance against toxic pollutants. Furthermore, melatonin improves the uptake of nitrogen (N), phosphorus (P), and sulfur (S) in stress situations, enhancing cell metabolism. In light of the above, the application of melatonin seems to be a useful option for clearing toxic pollutants from the environment by improving phytoremediation. Interestingly, a variety of stressors induce melatonin biosynthesis in plants, and the study of this endogenous response in hyperaccumulator plants may be even more interesting as a natural response of the phytoremediation of diverse plants.

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Exogenous Melatonin Improves Plant Iron Deficiency Tolerance via Increased Accumulation of Polyamine-Mediated Nitric Oxide

Cited by 88 publications

References 56 publications

Phytomelatonin: Recent advances and future prospects

Phytomelatonin: Recent advances and future prospects

Melatonin-Nitric Oxide Crosstalk and Their Roles in the Redox Network in Plants

Role of Melatonin to Enhance Phytoremediation Capacity

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