1998
DOI: 10.1016/s0945-053x(98)90117-2
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Exogenous non-crosslinked collagen enhances granulation tissue formation in dermal excision wounds in guinea pigs

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Cited by 7 publications
(5 citation statements)
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“…Several animal models have been used with success, to study the effects of growth factors on dermal wound healing. These models include mice,1, 11–15 rats,5, 14, 16–20 rabbits,12, 21–25 guinea pigs,3, 11, 15, 17, 26–35 and pigs 11, 30, 36–40. When choosing a laboratory animal for a dermal wound healing study, one has to consider certain aspects, which are associated with a particular animal.…”
Section: Introductionmentioning
confidence: 99%
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“…Several animal models have been used with success, to study the effects of growth factors on dermal wound healing. These models include mice,1, 11–15 rats,5, 14, 16–20 rabbits,12, 21–25 guinea pigs,3, 11, 15, 17, 26–35 and pigs 11, 30, 36–40. When choosing a laboratory animal for a dermal wound healing study, one has to consider certain aspects, which are associated with a particular animal.…”
Section: Introductionmentioning
confidence: 99%
“…A variety of wound types have been used in dermal wound‐healing research. These can be divided into incisional wounds, which are closed after wounding,14, 16, 18, 25 or excisional wounds 1, 3, 5, 11–15, 17–24, 26–29, 31–40. The method of creation of the wound can also vary.…”
Section: Introductionmentioning
confidence: 99%
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“…Pacini et al reported that the intravenous injection of CP enhanced the rate of collagen synthesis (6). Further more, CP promotes both procollagen type I biosynthesis and the repair process in a dermal wound (7). There fore, it seems possible that the structure and function of tendon are also affected by the ingestion of CP because collagen is a major component of tendon.…”
Section: Discussionmentioning
confidence: 99%
“…5 Meanwhile, it was postulated that collagen peptide could promote both procollagen type I biosynthesis and the repair process in a dermal wound. 6 Furthermore, in vitro studies have suggested that the NH2-or COOHterminal propeptides of collagens, once removed from their parent procollagen molecules, may exhibit specific regulatory activities; including among these is the influence of propeptides on the synthesis of collagen itself. [7][8][9] A subfragment of type I collagen with a minimum necessary sequence of KTTKS (Lys-Thr-Thr-Lys-Ser) has been reported to dramatically augment ECM production in fibroblasts.…”
Section: Introductionmentioning
confidence: 99%