Exophytic hepatocellular carcinoma, simulating a mesenchymal tumor, in a non-cirrhotic liver

Siqueira, Glaucio Rodrigo Silva de; Guimarães, Marcos Duarte; Franco, Luiz Felipe Sias; Coutinho, Rafaela Batista e Silva; Marchiori, Edson

doi:10.1590/0100-3984.2015.0118

Cited by 5 publications

(2 citation statements)

References 16 publications

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“…Magnetic resonance imaging (MRI) is another important method for the diagnosis of HCC ( 20 - 23 ) . Some functional MRI parameters, especially those determined with diffusion-weighted imaging (DWI), have also been investigated as potential predictors of outcomes in patients with HCC.…”

Section: Discussionmentioning

confidence: 99%

Microvascular invasion in hepatocellular carcinoma: is it predictable with quantitative computed tomography parameters?

et al. 2019

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Objective To investigate whether quantitative computed tomography (CT) measurements can predict microvascular invasion (MVI) in hepatocellular carcinoma (HCC).Materials and Methods This was a retrospective analysis of 200 cases of surgically proven HCCs in 125 consecutive patients evaluated between March 2010 and November 2017. We quantitatively measured regions of interest in lesions and adjacent areas of the liver on unenhanced CT scans, as well as in the arterial, portal venous, and equilibrium phases on contrast-enhanced CT scans. Enhancement profiles were analyzed and compared with histopathological references of MVI. Univariate and multivariate logistic regression analyses were used in order to evaluate CT parameters as potential predictors of MVI.Results Of the 200 HCCs, 77 (38.5%) showed evidence of MVI on histopathological analysis. There was no statistical difference between HCCs with MVI and those without, in terms of the percentage attenuation ratio in the portal venous phase (114.7 vs. 115.8) and equilibrium phase (126.7 vs. 128.2), as well as in terms of the relative washout ratio, also in the portal venous and equilibrium phases (15.0 vs. 8.2 and 31.4 vs. 26.3, respectively).Conclusion Quantitative dynamic CT parameters measured in the preoperative period do not appear to correlate with MVI in HCC.

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Section: Discussionmentioning

confidence: 99%

Microvascular invasion in hepatocellular carcinoma: is it predictable with quantitative computed tomography parameters?

et al. 2019

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“…The increasing use of imaging examinations for abdominal evaluation and recent technical advances in radiology have led to an increase in the number of liver lesions detected. The evaluation of the liver by imaging methods has been the subject of a series of recent publications in the radiology literature of Brazil ( 1 - 10 ) . Most liver lesions are benign and can be diagnosed on the basis of their imaging characteristics ( 11 ) .…”

Section: Introductionmentioning

confidence: 99%

Fat-containing liver lesions: a pictorial review

et al. 2018

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The aim of this pictorial essay is to review the spectrum of fat-containing liver lesions and their characterisation on magnetic resonance imaging with focus on the radiological features that aid in the differential diagnoses. Fat-containing liver lesions comprise a heterogeneous group of tumours with variable imaging findings. Magnetic resonance imaging clearly displays the micro- and macroscopic fat components of the lesions and other characteristic features that are helpful tools to make the differential diagnosis.

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Giant pedunculated liver mass: primary hepatocellular carcinoma masquerading as hepatic haemangioma

Cohen¹,

Aleem²,

Wolberink³

et al. 2021

BMJ Case Rep

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A woman in her mid-60s was referred to surgeons with a 2-week history of worsening right-sided abdominal pain. CT demonstrated a large encapsulated, pedunculated hepatic lesion with active intracapsular bleeding and free fluid but nil further lesions. Findings suggested giant hepatic haemangioma; surgical excision took place the following day. Histopathology however confirmed malignancy. Pedunculated hepatocellular carcinoma (HCC) is rare but characteristically large and encapsulated. Sporadic case reports indicate that diagnosis is typically challenging and delayed with liver metastases at presentation. This case describes a patient with no clear risk factors for HCC found to have a well-defined, encapsulated and pedunculated mass but no detected metastasis or other lesions on initial CT. In this instance, subsequent MRI did identify further lesions in the liver. Such cases are limited in the literature: much remains to be learnt regarding presentation, differential diagnoses, investigation and management.

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Exophytic hepatocellular carcinoma, simulating a mesenchymal tumor, in a non-cirrhotic liver

Cited by 5 publications

References 16 publications

Microvascular invasion in hepatocellular carcinoma: is it predictable with quantitative computed tomography parameters?

Microvascular invasion in hepatocellular carcinoma: is it predictable with quantitative computed tomography parameters?

Fat-containing liver lesions: a pictorial review

Giant pedunculated liver mass: primary hepatocellular carcinoma masquerading as hepatic haemangioma

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