Exosomal miR-4516 derived from ovarian cancer stem cells enhanced cisplatin tolerance in ovarian cancer by inhibiting GAS7

Pan, Xin; Shi, Xiu; Zhang, Hong; Chen, YouGuo; Zhou, JinHua; Shen, FangRong; Wang, Juan; Jiang, Rong

doi:10.1016/j.gene.2024.148738

Gene

2024

DOI: 10.1016/j.gene.2024.148738

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Exosomal miR-4516 derived from ovarian cancer stem cells enhanced cisplatin tolerance in ovarian cancer by inhibiting GAS7

Xin Pan,

Xiu Shi,

Hong Zhang

et al.

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Roles of miRNAs in regulating ovarian cancer stemness

Chong

2024

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

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Roles of miRNAs in regulating ovarian cancer stemness

Chong

2024

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

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Evolving landscape of detection and targeting miRNA/epigenetics for therapeutic strategies in ovarian cancer

Dey Bhowmik,

Shaw,

Gopinatha Pillai

et al. 2025

Cancer Letters

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Emerging strategies to overcome ovarian cancer: advances in immunotherapy

Massariol Pimenta,

Carlos de Souza,

da Silva Martins

et al. 2024

Front. Pharmacol.

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Ovarian cancer is the second most common malignant neoplasm of gynecological origin and the leading cause of death from cancer in the female reproductive system worldwide. This scenario is largely due to late diagnoses, often in advanced stages, and the development of chemoresistance by cancer cells. These challenges highlight the need for alternative treatments, with immunotherapy being a promising option. Cancer immunotherapy involves triggering an anti-tumor immune response and developing immunological memory to eliminate malignant cells, prevent recurrence, and inhibit metastasis. Some ongoing research investigate potentially immunological advancements in the field of cancer vaccines, immune checkpoint blockade, CAR-T cell, and other strategies.

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Exosomal miR-4516 derived from ovarian cancer stem cells enhanced cisplatin tolerance in ovarian cancer by inhibiting GAS7

Cited by 3 publications

References 39 publications

Roles of miRNAs in regulating ovarian cancer stemness

Roles of miRNAs in regulating ovarian cancer stemness

Evolving landscape of detection and targeting miRNA/epigenetics for therapeutic strategies in ovarian cancer

Emerging strategies to overcome ovarian cancer: advances in immunotherapy

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