2024
DOI: 10.1128/jvi.01519-24
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Exosome-mediated viral nucleic acid presentation in a crustacean expounds innate immunity from a novel perspective

Yi Gong,
Hang Hu,
Xinshan Zhao
et al.

Abstract: As an enduring hot topic in the field of innate immunity, apoptosis is widely considered an effective approach to eliminate pathogenic microbes and plays a crucial role during host–pathogen interactions. Recently, researchers have found that the virus-containing host cells could transmit apoptotic signals to the surrounding uninfected cells during infection, but the mechanism remains unclear. Here, we found that exosomes secreted by WSSV-infected mud crab hemocytes contain viral nucleic acid wsv277, which coul… Show more

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