Expanded Endoscopic Endonasal Approach for Treatment of Clival Chordomas

Dehdashti, Amir R.; Karabatsou, Konstantina; Ganna, Ahmed; Witterick, Ian J.; Gentili, Fred

doi:10.1227/01.neu.0000316414.20247.32

Cited by 149 publications

(109 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1,5,9,20 This EEA shows almost equivalent results to extensive approaches. 21,22 The complication of CSF leak can be managed with local flap repair techniques. Hence, this approach should be in the surgery of choice for the management of clival chordomas.…”

Section: 12mentioning

confidence: 99%

“…[20][21][22] Conventional radiotherapy with high-energy photons at a dose of 60 to 65 Gy may offer temporary benefit in disease control in patients with inadequate surgery or recurrence or as exclusive treatment for inoperable disease. 22 Prognosis of the tumor is typically poor, due to the locally aggressive nature of these tumors, with the 10-year survival approximately 40%. 2,17,22 …”

Section: 12mentioning

confidence: 99%

See 1 more Smart Citation

Endoscopic Removal of Clival Chordoma

Yadav¹,

Kumar²,

Selvaraj³

et al. 2017

An International Journal Clinical Rhinology

View full text Add to dashboard Cite

Clivus chordomas are locally aggressive benign, with primary bone tumor arising from remnant of notochord anywhere from the coccyx to the base of the skull, in either a midline or paramedian position. The tumors show rare presentation and relatively common recurrence rate. Intracranial chordomas usually arise from the region around the clivus and account for about a third of all chordomas. Clival chordomas rarely metastasize and become symptomatic after local invasion to cranial nerves and skull base structure. Diagnosis is based on computed tomography scan/magnetic resonance imaging findings and histopathological examination of soft tissue mass. Complete surgical resection is the primary line of management with or without radiotherapy. We are presenting a case of clival chordoma of a 35-year-old female who presented with diminished vision and headache since 6 months. After evaluation, the patient was treated with endoscopic endonasal transsphenoidal resection of the tumor. After surgery, the patient showed relief from headache and slight improvement in vision loss.

show abstract

Section: 12mentioning

confidence: 99%

Section: 12mentioning

confidence: 99%

Endoscopic Removal of Clival Chordoma

Yadav¹,

Kumar²,

Selvaraj³

et al. 2017

An International Journal Clinical Rhinology

View full text Add to dashboard Cite

show abstract

“…For example, Fraser et al [ 44 ] achieved > 95% tumor resection in seven (87%) of eight patients in whom complete tumor resection was the goal. Stippler et al [ 117 ] and Dehdashti et al [ 27 ] reported GTR resection rates for clival chordomas of 67% and 58% with CSF leak rates of 25% and 33%, respectively. Carrabba et al [ 11 ] found reduced levels of postoperative morbidity in patients treated via an endonasal endoscopic approach for clival lesions as compared to those who underwent open resection.…”

Section: Clival Chordomasmentioning

confidence: 99%

Transsphenoidal endoscopic skull base surgery: state of the art and future perspective

Cutler

Barkhoudarian

Griffiths³

et al. 2013

Innovative Neurosurgery

View full text Add to dashboard Cite

Given refinements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques and anatomical understanding, the endonasal endoscopic approach is now a well-accepted and widely utilized technique for removal of many if not most midline ventral skull base tumors. Pituitary adenomas and Rathke ' s cleft cysts (RCCs) constitute the majority of lesions removed via this route; however, craniopharyngiomas, clival chordomas, midline meningiomas and other benign and malignant skull base tumors are now increasingly removed by this approach. Herein we describe the evolution of the endonasal endoscopic technique, its current use for sellar and midline skull base tumors and potential for future innovation.

show abstract

“…1 The expanded endonasal approach (EEA) and its modifications provide access to the anterior skull base, planum, sphenoid, sella, clivus, cervical spine, and infratemporal fossa via the two nostrils. [2][3][4][5][6][7][8][9] This approach enables endoscopic extradural and intradural tumor resection and skull base reconstruction in a single procedure.…”

Section: Introductionmentioning

confidence: 99%