2023
DOI: 10.3389/fimmu.2023.1229520
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Expanded population of low-density neutrophils in juvenile idiopathic arthritis

Zuzana Parackova,
Irena Zentsova,
Marketa Bloomfield
et al.

Abstract: IntroductionJuvenile idiopathic arthritis (JIA), a clinically variable disease characterized by autoimmune arthritis, affects children, and its immunopathology remains elusive. Alterations in neutrophil biology play an important role in this disease. In the present study, we aimed to explore the features of low-density neutrophils (LDNs) in patients with JIA.MethodsGene expression of peripheral blood mononuclear cells (PBMCs) from children with distinct subtypes of JIA was analyzed by NanoString Immunology pan… Show more

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