“…Several light-based cancer treatment methods have been reported, including photodynamic therapy, photothermal therapy, and near-infrared (NIR) photoimmunotherapy (NIR-PIT). 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 Of these, NIR-PIT, which received conditional approval in Japan in September 2020, has attracted increasing attention. NIR-PIT induces cell necrosis with high tissue selectivity and minimal side effects; 11 thus, it is expected to become the fifth clinical cancer treatment modality after surgery, chemotherapy, radiotherapy, and cancer immunotherapy.…”