Expansile gas concentration in primary pseudophakic retinal detachment repair, effect on intraocular pressure and outcomes; the Manchester Pseudophakic Retinal Detachment Study

Moussa, George; Jalil, Assad; Ivanova, Tsveta; Cristescu, Irina-Elena; Ferrara, Mariantonia; Lippera, Myrta; Jasani, Kirti M; Dhawahir-Scala, Felipe; Patton, Niall

doi:10.1007/s00417-023-06067-4

Cited by 3 publications

(1 citation statement)

References 26 publications

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“…The SSAS for primary PPV in RD with inferior retinal breaks in detached retina ranges from 76% to 95.4% in the literature. 18,19,22 Our higher success rate may be attributed to several factors, including the exclusion of proliferative vitreoretinopathy C or giant retinal tears and the inclusion of only pseudophakic eyes. Indeed, patients with PRD are known to have favorable anatomical outcomes, and this has been attributed to the better view and peripheral retinal access allowing for an improved peripheral vitreous shave and, thus, increased volume of gas tamponade.…”

Section: Discussionmentioning

confidence: 98%

SF6 compared to C2F6 for inferior rhegmatogenous retinal detachment repair; The Manchester Pseudophakic Retinal Detachment Study

Moussa,

Jalil,

Lippera

et al. 2024

Retina

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Purpose- To compare SF6 relative to C2F6 in the anatomical and functional outcomes following pars plana vitrectomy (PPV) for uncomplicated primary pseudophakic rhegmatogenous retinal detachment (PRD) with inferior causative breaks. Methods- This is a retrospective, comparative study on eyes with PRD with inferior causative breaks that had small-gauge PPV repair using SF6 and C2F6 tamponade between 2011-2020 at a tertiary centre in the UK. Primary outcome was single surgery anatomical success (SSAS) and the secondary outcomes, best-corrected visual acuity (BCVA). Propensity score matching (PSM), using preoperative findings as covariates to account for relevant confounders, was performed. Results- From 162 PRD eyes with inferior causative breaks, the median (interquartile range) follow-up was 82 (52-182) days. The SSAS was 156 (96.3%) overall; 47/47 (100.0%) and 109/115 (94.8%) in the SF6 and C2F6 groups, respectively (p=0.182). Relative to the SF6 group, the C2F6 group had a higher mean number of tears (SF6:3.1[2.0], C2F6:4.5[2.7], p=0.002) and greater RD extent (SF6:5.3[2.9], C2F6:6.2[2.6] clock hours, p=0.025). Following PSM analysis, 80 eyes were matched with 40 in each group to homogenise preoperative factors. No significant difference was found in SSAS and BCVA between groups following PSM. Conclusions- Primary PPV with gas tamponade leads to a high SSAS rate in uncomplicated PRD with inferior causative breaks with no additional benefit associated with long-acting tamponade when comparing C2F6 with SF6.

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Section: Discussionmentioning

confidence: 98%

SF6 compared to C2F6 for inferior rhegmatogenous retinal detachment repair; The Manchester Pseudophakic Retinal Detachment Study

Moussa,

Jalil,

Lippera

et al. 2024

Retina

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Thirteen year experience of vitrectomy and air tamponade for primary retinal detachment repair with clinical outcomes

Mete,

Maggio,

Prigione

et al. 2024

Sci Rep

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Purpose To report outcomes of pars plana vitrectomy (PPV) with air tamponade for primary rhegmatogenous retinal detachment (RRD) and investigate the impact of vitreous cortex remnants (VCR) on surgical outcomes. Methods A retrospective review of 900 patients treated for uncomplicated primary RRD between 2007 and 2020. Exclusion criteria included axial length > 26 mm, prior retinal surgery, giant retinal tear, PVR grade > B, and inadequate follow-up. Primary outcomes were retinal reattachment rate and best-corrected visual acuity (BCVA). Results Of 900 patients, 397 met inclusion criteria. Primary reattachment rate was 88.4%, with significant BCVA improvement. Forty-six eyes experienced RRD recurrence. Complications included cataracts (38.8%), IOP rise (11.4%), and macular edema (8.3%). Better final BCVA was associated with preoperative macular non-involvement and absence of reinterventions. No significant association was found between RRD recurrence and various factors, including VCR removal. Conclusion Air tamponade is a safe and effective option for primary RRD treatment. It has no negative effect on the environment and creates less discomfort for patients. VCR removal did not significantly reduce RRD recurrence in the overall number of cases. Further research will help determine the role of VCR in RD recurrence and define in which cases their removal might be beneficial.

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Incidence of early complications requiring treatment plan changes after vitreoretinal surgery: a single-center study in South Korea

Yoon

Kim

et al. 2023

BMC Ophthalmol

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Background Information regarding incidence of treatment plan changes may be useful when discussing postoperative treatment plans for patients. Moreover, it may help establish a standardized postoperative treatment plan. This study aimed to evaluate the incidence of early complications requiring treatment plan changes in patients following vitreoretinal surgery and investigate its risk factors. Methods This single-center retrospective study included 465 patients who had undergone vitreoretinal surgery. The reasons, incidence, and timing of treatment plan changes within 14 days of surgery were identified. Potential factors associated with the changes, such as patient demographics, surgeon’s experience, diagnoses, and type of surgery were also analyzed. Results The treatment plan was changed in 76 patients (16.3%) at a mean of 4.0 ± 3.2 days after vitreoretinal surgery. The reasons for the plan changes were increased intraocular pressure (IIOP) in 66(86.8%), intraocular inflammation in 2(2.6%), corneal edema in 3(3.9%), leakage from the sclerotomy wound in 3(3.9%) patients, and combined IIOP and intraocular inflammation in 2(2.6%). The date of discharge was postponed because of treatment plan changes in 17 patients (22.4%). The incidence of plan changes was higher in patients who underwent gas or oil tamponade (P < 0.001) and those who underwent surgery performed by less experienced surgeons (P = 0.034). Conclusions Treatment plan was changed in 16.3% of patients after vitreoretinal surgery. The risk of treatment plan changes was associated with the surgeon’s experience in vitreoretinal surgery and the type of surgery. These results should be considered when establishing standardized care plans for patients who require vitreoretinal surgery.

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Expansile gas concentration in primary pseudophakic retinal detachment repair, effect on intraocular pressure and outcomes; the Manchester Pseudophakic Retinal Detachment Study

Cited by 3 publications

References 26 publications

SF6 compared to C2F6 for inferior rhegmatogenous retinal detachment repair; The Manchester Pseudophakic Retinal Detachment Study

SF6 compared to C2F6 for inferior rhegmatogenous retinal detachment repair; The Manchester Pseudophakic Retinal Detachment Study

Thirteen year experience of vitrectomy and air tamponade for primary retinal detachment repair with clinical outcomes

Incidence of early complications requiring treatment plan changes after vitreoretinal surgery: a single-center study in South Korea

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