“…Experimental evidence from caffeine studies employing a placebo design has demonstrated that altered physiological (e.g., Lotshaw, Bradley, & Brooks, 1996; Mikalsen, Bertelsen, & Flaten, 2001), emotional (e.g., Haskell et al, 2005), cognitive (e.g., Christensen, White, Krietsch, & Steele, 1990; Oei & Hartley, 2005), and even neurobiological (e.g., Kaasinen, Aalto, Nagren, & Rinne, 2004) responses following a caffeine or placebo challenge, are influenced by caffeine expectancies. For example, Fillmore and Vogelsprott (1992) found that participants who expected that caffeine would either impair or enhance performance on a motor-pursuit task performed in accordance with their respective expectations for drug effects in both placebo and caffeine conditions.…”