Expectations and quality of life of cancer patients undergoing radiotherapy

Koller, Michael; Lorenz, W.; Wagner, Katja; Keil, A.; Trott, D.; Engenhart‐Cabillic, Rita; Nies, C.

doi:10.1177/014107680009301205

Cited by 63 publications

(49 citation statements)

References 35 publications

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“…The COMQ-12 is a patient-related outcomes questionnaire that is constructed to obtain information about the symptoms that are most important for the patient. It allows the clinician to get an idea of the expectations of patients regarding therapy and to choose an adequate management strategy that is consistent with these expectations [7] . We translated the original COMQ-12 into Dutch and tested it for validity, diagnostic accuracy, and test-retest reliability.…”

Section: Discussionmentioning

confidence: 99%

Validity and Test-Retest Reliability of the Dutch Version of the Chronic Otitis Media Questionnaire 12 (COMQ-12)

J¹,

Droessaert²,

Camp³

et al. 2016

Int Adv Otol

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OBJECTIVE:To test the validity and test-retest reliability of the Dutch translation of the Chronic Otitis Media Questionnaire 12 (COMQ-12). MATERIALS and METHODS:Thirty-five healthy individuals with no history of chronic otitis media (COM) received the questionnaire as well as a group of 35 patients with complaints of COM. The healthy participants had to complete the questionnaire twice (control group 1 and control group 2) to estimate the test-retest reliability, and their scores were compared with those of the patients (group 3) to test the validity. RESULTS:The overall COMQ-12 score in control group 1 ranged from 0 to 11, in control group 2 from 0 to 6, and in group 3 from 7 to 46. The mean score in control group 1 was 1.43 [standard deviation (SD) 2.30], 1.34 in control group 2 (SD 2.06), and 27.80 in group 3 (SD 10.51). A comparison of the absolute COMQ-12 scores of the two control groups and the patient group showed a significantly higher COMQ-12 score in patients with COM than in controls. The diagnostic accuracy was investigated, and a COMQ-12 cut-off score of 8 was found to have a near-perfect sensitivity and specificity in distinguishing between the presence and absence of COM. The single-measures intraclass correlation coefficient for absolute agreement (ICCAA) was 0.859 (with a 95% confidence interval from 0.738 to 0.926). This clearly exceeded the ICC threshold for acceptable reliability (ICC≥0.75) and therefore confirmed that there was reasonable test-retest reliability when applying the questionnaire to control subjects. CONCLUSION:The Dutch version of the COMQ-12 has good validity, diagnostic accuracy, and test-retest reliability.

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Section: Discussionmentioning

confidence: 99%

Validity and Test-Retest Reliability of the Dutch Version of the Chronic Otitis Media Questionnaire 12 (COMQ-12)

J¹,

Droessaert²,

Camp³

et al. 2016

Int Adv Otol

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“…Roscoe et al 261 examined treatment-related nausea in chemotherapy patients and reported, on the basis of two small studies, that there was a significant association between patients' pretreatment expectations of nausea and severity of nausea post chemotherapy. In Koller et al 's study 124 of expectations, quality of life and clinical variables with a sample of hospital inpatients receiving radiotherapy, quality of life was found to be altered little by radiotherapy but became substantially worse in the group who had expected healing but perceived that this had failed (even though physician-assessed Karnofsky performance status had not changed), although the authors do note that the exact temporal sequence of healing expectations and quality of life was not tested.…”

Section: Expectancy Itemsmentioning

confidence: 98%

The measurement of patients’ expectations for health care: a review and psychometric testing of a measure of patients’ expectations.

Bowling

Rowe²,

Lambert³

et al. 2012

Health Technol Assess

254

251

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How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address.Paying by credit card You can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume.How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment programmeThe Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service' . The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of project...

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“…Recently these classical endpoints in clinical trials were supplemented by new (hermeneutic) endpoints [1] like quality of life, expectations and negative affect as psychological basic variables self-reported by patients [2,3]. For this reason, the clinical scenario should be modelled as accurate as possible in animal trials including an equivalent of quality of life in animals.…”

Section: Introductionmentioning

confidence: 99%

Quality of Life in Animals as a New Outcome for Surgical Research: G-CSF as a Quality of Life Improving Factor

Bauhofer¹,

Witte

Middeke³

et al. 2002

Eur Surg Res

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Sepsis is still a major problem in human medicine with a high mortality rate. Nearly all attempts to improve the outcome of septic patients with immune modulators failed. In most of these trials only mechanistic endpoints such as mortality rate, complication rate, cytokine levels and physiological parameters were assessed. Only in a very few trials quality of life had been chosen as primary endpoint. In basic research and especially in animal experiments in the field of sepsis and oncology, only molecular investigations which explain drug and treatment interactions were in the focus of the scientific community. Animal models simulating clinical complexity and investigating outcomes like quality of life were very rare. The aim of this study was to demonstrate alterations in sickness behaviour – the animal equivalent to quality of life in man – in rats as a response to sepsis after prophylaxis with G-CSF and antibiotics. Sickness behaviour was assessed by measurement of core body temperature, food and water intake, locomotor activity and circadian rhythm of these parameters. Complex animal experiments in rats were performed including anaesthesia, antibiotic and cytokine (G-CSF) prophylaxis, volume substitution, laparotomy, contamination and infection with human faecal suspension and postoperative analgesia. In group A (sham) and D (antibiotic + G-CSF) the mortality rate was 0% , but in group B (no prophylaxis) 33% (3/9) and in group C (antibiotic prophylaxis) 11% (1/9) of the animals died. Before infection all rats showed clear circadian patterns of locomotor activity and body temperature with physiologically higher values during the night-time. Immediately after operation and infection temperature increased, water and food intake, locomotor activity decreased and circadian rhythms were lost. Body temperature and water consumption were already normalised at day 2 after infection in all groups. Normal food intake was re-established in group C and D at day 3 while one more day was needed for recovery in Group C. Restoration of locomotor activity occurred in group D at day 5, in group C at day 7. In group B locomotor activity remained suppressed during the whole observation period of 8 days postoperatively. In conclusion, in septic rats sickness behaviour, an equivalent to quality of life in humans, is improved rapidly by a prophylaxis with G-CSF in combination with antibiotics and can be used as a new outcome in preclinical surgical research.

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Expectations and quality of life of cancer patients undergoing radiotherapy

Cited by 63 publications

References 35 publications

Validity and Test-Retest Reliability of the Dutch Version of the Chronic Otitis Media Questionnaire 12 (COMQ-12)

Validity and Test-Retest Reliability of the Dutch Version of the Chronic Otitis Media Questionnaire 12 (COMQ-12)

The measurement of patients’ expectations for health care: a review and psychometric testing of a measure of patients’ expectations.

Quality of Life in Animals as a New Outcome for Surgical Research: G-CSF as a Quality of Life Improving Factor

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