Expectoration of a bronchogenic carcinoma

Spontaneous Expectoration of Tumor Tissue in a Patient With Adenocarcinoma of the Lung

“…Since Walshe et al described expectorated tumor fragments in sputum in 1843, 1 30 cases have been reported (Table). The most frequent tumor was renal cell carcinoma (8 cases, 26.7%), 10 -13,15 followed by primary lung cancer and sarcoma (7 cases each, 23.3% each).…”

“…Endobronchial metastases from various organs are most common, although 9 primary lung cancer cases have been described, including 4 squamous cell carcinomas, 2 bronchogenic carcinoids, one small cell lung carcinoma, one large cell carcinoma, and one mixed type carcinoma. [1][2][3][4][5][6][7][8][9] Adenocarcinoma of the lung has never been reported. We describe a case of spontaneous expectoration of a piece of lung adenocarcinoma, which enabled a definitive diagnosis of a local recurrence, and led to substantial relief from dyspnea.…”

Spontaneous expectoration of pulmonary metastases in a child with osteogenic sarcoma

“…Most common metastatic cancers presenting as expectoration were renal cell carcinoma, [4][5][6][7] colon cancer, 8,9 and fibrosarcomas, 10,11 while common lung primary cancers presenting with expectoration include squamous cell carcinoma, small cell lung cancer, bronchogenic carcinoids, and primary sarcoma of lungs. [12][13][14][15][16] Expectoration of the primary lung cancer occurs because of exfoliation of free tumor fragments in the airway. But endobronchial metastases expectorate by releasing tissue into the airway after treatment-related ulceration and necrosis.…”

“…Expectoration of tumor tissue is a very rare event with only 30 reported cases in the literature, predominantly from metastatic cancers and only a few primary lung cancers. Most common metastatic cancers presenting as expectoration were renal cell carcinoma, colon cancer, and fibrosarcomas, while common lung primary cancers presenting with expectoration include squamous cell carcinoma, small cell lung cancer, bronchogenic carcinoids, and primary sarcoma of lungs . Expectoration of the primary lung cancer occurs because of exfoliation of free tumor fragments in the airway.…”

Endobronchial Tumor Migration Presenting with Acute Breathlessness and Stridor

“…Expectoration of tumor has previously been reported, [1][2][3][4][5][6] but not in relation to the relief of acute airways obstruction.…”