Experience and levels of satisfaction with the levonorgestrel-releasing intrauterine system in China: a prospective multicenter survey

Zhao, Shuping; Ji-hong, Deng; Wang, Yan; Bi, Shiliang; Wen, Qin; Huang, Zengshu; Li, Li; Mi, Xin; Liang, Han; Chang, Qing; Li, Jian

doi:10.2147/ppa.s68299

Cited by 8 publications

(13 citation statements)

References 11 publications

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“…Similarly, Abraham et al found that nulliparous women were more likely to discontinue Cu-IUS and implants than parous, but it was not reported for the group consisting of LNG-IUS users [30]. This finding was also confirmed by other authors [32,49,52]. In a study conducted by Teunissen et al, continuation rates in women with parity ≥ 2 were noticeably higher than in nulliparous ones at all follow-up visits (first year-77% vs. 81%; second year-64% vs. 72%; third year-50% vs. 65%; fourth year-38% vs. 59%; fifth year-11% vs. 24%; authors did not specify the level of statistical significance for those differences) [47].…”

Section: Continuationmentioning

confidence: 68%

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Levonorgestrel-Releasing Intrauterine System as a Contraceptive Method in Nulliparous Women: A Systematic Review

Zgliczyńska

Kocaj

Szymusik

et al. 2020

JCM

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The aim of this review was to summarize the available evidence about the use of levonorgestrel-releasing intrauterine system (LNG-IUS) as a contraceptive method in nulliparous women. For this purpose, studies evaluating the efficacy, safety, bleeding pattern, satisfaction and discontinuation of the levonorgestrel-releasing intrauterine system in nulliparous women were analyzed. Only original research articles published in English between 1990–27th March 2020 were considered eligible. Reviews, book chapters, case studies, conference papers, opinions, editorials and letters were excluded. The systematic literature search of PubMed/MEDLINE, Scopus, Embase and Cochrane Library databases identified 816 articles, 23 of which were analyzed. The available evidence indicates that LNG-IUS is an effective and safe contraceptive method for nulliparous women that achieves high levels of satisfaction among patients. Moreover, nulliparous women seem to experience fewer expulsions than parous ones. Bleeding pattern is acceptable for the majority of patients, and bleeding disorders mainly occur in the first months after the insertion. More in-depth, long-term prospective studies are needed in this patient group to determine risk factors for the occurrence of side effects and associated discontinuations, which should not, however, delay the wider use of the method in this group, given the number of advantages.

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Section: Continuationmentioning

confidence: 68%

“…A total of 15 out of 23 articles reported data on the continuation rates in the studied population [30][31][32][35][36][37]39,41,43,45,[47][48][49]51,52] (Table 3). In the studies assessing the rate of continuing treatment after the first year, continuation rates ranged from 73% (Kaislasuo et al) up to 93% (Hall et al).…”

Section: Continuationmentioning

confidence: 99%

Levonorgestrel-Releasing Intrauterine System as a Contraceptive Method in Nulliparous Women: A Systematic Review

Zgliczyńska

Kocaj

Szymusik

et al. 2020

JCM

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“…Later, the copper-releasing IUDs replaced the steel rings as many problems were encountered by using the rings [ 29 ].Nowadays, copper-releasing IUDs have become the prevailing devices in clinical application in China [ 22 , 24 ]. Recently, the levonorgestrel intrauterine system (LNG-IUS) along with other optimized IUDs were also provided to Chinese women [ 25 ]. In this study, the majority of devices that induced uterine perforation were copper-releasing IUDs with T-shaped copper ( n = 10) followed by V-shaped copper IUDs ( n = 13) and four of those with O-shaped IUDs (Table 1 ).…”

Section: Discussionmentioning

confidence: 99%

“…Most of the IUDs used in China are manufactured in China, and the majority is the copper-releasing IUDs, including all types of T-shaped and V-shaped copper-releasing IUDs. Recently, some overseas products, as LNG-IUS [ 25 ] and GyneFix [ 26 ], have also been introduced to China.…”

Section: Introductionmentioning

confidence: 99%

Clinical characteristic and intraoperative findings of uterine perforation patients in using of intrauterine devices (IUDs)

et al. 2018

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BackgroundIntrauterine devices (IUDs) are the most popular form of contraception used worldwide; however, IUD is not risk-free. IUD migrations, especially uterine perforations, were frequently occurred in patients. The aim of this study was to investigate the clinical characteristics and intraoperative findings in patients with migrated IUDs.Results29 cases of uterine perforation associated with migrated IUDs and 69 control patients were followed between January 2008 to March 2015. Patients who used IUDs within first 6 months from the last delivery experienced a characteristically high rate of the perforation of the uterine wall. A significantly larger number of IUD insertion associated with uterine perforation were performed in rural hospitals or operated at a lower level health care system. There was no clear difference in the age and presented symptoms in patients between two groups. Majority of contraceptive intrauterine devices was the copper-releasing IUDs. Furthermore, patients who used V-shaped IUD showed significantly higher incidence of pelvic adhesions when compared with the users of O-shaped IUDs.ConclusionsUnique clinical characteristics of IUD migration were identified in patients with uterine perforation. Hysteroscopy and/or laparoscopy were the effective approaches to remove the migrated IUDs. Improving operating skills is required at the lower level of health care system.

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“…Similar to this study, previous studies from Western countries have reported a lack of awareness and misconceptions among HCPs regarding the unsuitability of IUD in certain groups of women, levying a substantial impact on the IUD use [ 19 ]. In addition, LNGIUS use in this study was low (0.5%), despite its availability in the Chinese market since 2000 and high satisfaction rates among Chinese women [ 20 ]. The reason for the low prevalence may be the high price, which is not covered under the health insurance schemes.…”

Section: Discussionmentioning

confidence: 99%

Practices and knowledge of female gynecologists regarding contraceptive use: a real-world Chinese survey

Yang

Wang

et al. 2018

Reprod Health

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BackgroundThere is no evidence of the practices of obstetricians and gynecologists (OB/GYNs) regarding contraceptive use and determinants influencing contraceptive choices, including emergency methods such as combined oral contraceptives (COCs) and levonorgestrel intrauterine system (LNGIUS). This survey determines the practices and knowledge among Chinese female OB/GYNs regarding modern contraceptive methods.MethodsA multicenter questionnaire was completed by 2000 female OB/GYNs participating in training courses organized by the gynecological endocrinology training committee of the Chinese Medical Doctor Association from February to May 2013.ResultsThis survey achieved a response rate of 51.4%. The rate of induced abortion among this group was 56.3%; this may be attributable to unreliable contraceptive methods (55.5%) and failure of reliable contraceptive methods (18.9%). Intrauterine devices (IUDs) were more commonly used by parous women than nulliparous women (42.6% vs 1.7%; p < 0.0001), followed by condom and rhythm method (24.2% vs 20.8%). However, nulliparous women commonly used rhythm method (48.3% vs 3.3%; p < 0.0001) and condoms (19.2% vs 10.5%; p = 0.008). OB/GYNs demonstrated misconceptions of OB/GYNs about COCs, such as the risk of breast cancer, amenorrhea and premature ovarian failure, and decreased fertility as reported by 37.10, 10.6, and 7.5% of the respondents, respectively.ConclusionsIUDs were commonly used by parous Chinese OB/GYNs. Unreliable contraceptive methods and misconceptions about the side effects of COCs may result in the high rate of unintended pregnancies. Hence, awareness of safe and effective contraceptive methods should be strengthened among OB/GYNs in China.

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Experience and levels of satisfaction with the levonorgestrel-releasing intrauterine system in China: a prospective multicenter survey

Cited by 8 publications

References 11 publications

Levonorgestrel-Releasing Intrauterine System as a Contraceptive Method in Nulliparous Women: A Systematic Review

Levonorgestrel-Releasing Intrauterine System as a Contraceptive Method in Nulliparous Women: A Systematic Review

Clinical characteristic and intraoperative findings of uterine perforation patients in using of intrauterine devices (IUDs)

Practices and knowledge of female gynecologists regarding contraceptive use: a real-world Chinese survey

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