Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches

Ciernia, Annie Vogel; Laufer, Benjamin I.; Dunaway, Keith W.; Mordaunt, Charles E.; Coulson, Rochelle L.; Totah, Theresa S.; Stolzenberg, Danielle S.; Frahm, Jaime C.; Singh-Taylor, Akanksha; Baram, Tallie Z.; LaSalle, Janine M.; Yasui, Dag H.

doi:10.1101/191791

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Effects Of Parental Care or Affiliative Stimuli On The Oxytocin System1

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2021

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“…Postnatal maternal separation for a short duration (e.g., 1-15 min day -1 ) has been shown to reduce the hypothalamic oxytocin content in suckling rats 78 and to reduce the number of hypothalamic oxytocin neurons in adult rats. 79,80 Reduction of oxytocin content has also been reported in the amygdala of adult male rats.…”

Section: Effects Of Parental Care or Affiliative Stimuli On The Oxytocin Systemmentioning

confidence: 99%

The oxytocin system and early‐life experience‐dependent plastic changes

Onaka

Takayanagi

2021

J Neuroendocrinology

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Oxytocin is mostly synthesized within the hypothalamus and acts mainly on the oxytocin receptor that is expressed in the nervous system and peripheral organs. Oxytocin exerts not only reproduction-related functions such as delivery of children and milk ejection during the lactation period, but also various actions including control of stress-related responses, emotional responses and social behaviour. [1][2][3][4][5][6][7] The oxytocin receptor gene has single-nucleotide polymorphisms (SNPs) and SNPs of the oxytocin receptor gene have been shown to be associated with difference in pair bonding, 8 empathy and stress responsiveness, 9 generous

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Section: Effects Of Parental Care or Affiliative Stimuli On The Oxytocin Systemmentioning

confidence: 99%