A deep foundation pit in a station of the Hangzhou subway is adjacent to new high-rise residential buildings on the north side and to the Evergrande foundation pit being excavated on the south side. This work considers the excavation of the foundation pit in the subway station as the research subject, focuses on the difference of the deformation and Earth pressure between the north side and the south side of the foundation pit under these special working conditions through the analysis of the measured data, and compares it with an ordinary foundation pit. Analyzing the measured data reveals that the horizontal displacement of the retaining wall and the ground settlement are far larger on the north side than on the south side, and both often exceed the deformation alarm value; the deformation of the ordinary foundation pit is between the deformation of the overloaded (north) side and that of the unloaded (south) side of the foundation pit. Moreover, the maximum rate of the horizontal creep of the soil and the maximum rate of the creep caused by the ground settlement on the north side of the foundation pit are larger than those on the south side of the foundation pit; the maximum rate of the horizontal creep of the ordinary foundation pit is between the two. The active Earth pressure on the pit wall on the north side is higher than that on the south side of the foundation pit, and because of the surrounding unloading, passive Earth pressure is generated at the bottom of the pit wall on the south side of the foundation pit, which causes it to shift to the outside of the foundation pit. The settlement of the surrounding high-rise buildings and the settlement of the columns are all within the range of the alarm values; also, the buildings settle evenly. Due to the excavation and unloading on the south side of the foundation pit, the uplift of the columns is not considerable.