Experience in the use of high-frequency selective percutaneous rhizotomy in trigeminal neuralgia associated with multiple sclerosis

Abstract

These data confirm that PHFSR is a safe, repeatable, and effective method of symptomatic neurosurgical treatment of TN associated with MS and may be recommended in the case of failure/intolerance of medication.

Trigeminal neuralgia secondary to multiple sclerosis: from the clinical picture to the treatment options

“…Several studies with a follow-up exceeding one year have investigated the role of surgical procedures designed to lesion the Gasserian ganglion. Procedures were performed chemically by glycerol injections [61, 70–72], mechanically by balloon compression [73–76], or thermically by radiofrequency thermocoagulation [64, 77–79]. Although most patients enrolled in these studies reported complete acute pain relief following the lesioning procedures, the recurrence rate during follow-up and the frequency of adverse events varied widely (Table 1).…”

Association of Trigeminal Neuralgia with Multiple Sclerosis: A Comprehensive Review of Neuropathic Pain Treatment

“…Several studies with more than 1 year of follow-up have examined the role of surgical procedures in repairing damage to the gasserian ganglion. The procedures were performed chemically with glycerol injections (72-75), mechanically with balloon compression (76-79), or thermally (70,(80)(81)(82). Although most of the patients reported complete acute pain relief after the lesion procedures, the recurrence rate during follow-up and the incidence of adverse events varied widely.…”

“…A recent retrospective review of long-term outcomes in 42 patients showed that the incidence rates of cases with pain relief after SRS were 62%, 29%, 22%, and 13% after 1, 3, 5, and 7 years, respectively (89). Retrospective studies have compared the efficacy of SRS with gasserian ganglion surgery (74)(75)(76)(77)(78)(79)(80)(81)(82)(83)(84)(85)(86)(87)(88)(89)(90). These studies have shown that patients who underwent gasserian ganglion surgery experience immediate pain relief and no longer need to resort to AI therapies than patients treated with SRS.…”