Experience of a National Health Service Menopause Clinic

Moore, B.; Gustafson, Rolf; Studd, John

doi:10.1185/03007997509109275

Cited by 20 publications

(7 citation statements)

References 10 publications

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“…16 The lack of an association between sexual dysfunction and disappearance of menstruation is perhaps surprising; elsewhere increased sexual dysfunction has been reported among women attending a menopause clinic. 6 Nevertheless, attenders at such clinics may be unusual in several ways, and our results are consistent with those of an earlier postal survey ofwomen in the community. '7 The finding that operationally defined sexual dysfunction was not associated with a history of gynaecological surgery agrees with results from other prospective research.9 10 When a discriminant function analysis was done age emerged as the most important determinant of operationally defined dysfunction; neuroticism and poor quality of marriage also contributed but psychiatric case state did not.…”

Section: Discussionsupporting

confidence: 91%

“…From hospital practice there is evidence that sexual dysfunctions may be closely associated with both gynaecological symptoms5 6 and psychiatric disorder,' but nothing is known about these associations in the general population. Research findings are difficult to interpret because of problems of method, including use of atypical samples, low response rates, and lack ofclear operational definitions of sexual dysfunction.…”

Section: Introductionmentioning

confidence: 99%

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Sexual dysfunction among middle aged women in the community

Osborn¹,

Hawton²,

Gath³

1988

BMJ

197

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In a community survey of women aged 35-59 sexual functioning was studied in the 436 women with partners. One third of these women had operationally defined sexual dysfunction: impaired sexual interest was identified in 17% of women (68/406), vaginal dryness in 17% (73/434), infrequency of orgasm in 16% (60/379), and dyspareunia in 8% (30/379). Sexual dysfunctions were statistically significantly associated with increasing age and also with psychiatric disorder, neuroticism, and marital disharmony. One in 10 women regarded themselves as having a sexual problem. These women were no older than women with sexual dysfunction who did not regard themselves as having a sexual problem. Nevertheless, they differed from the rest of the sample in having more psychiatric disorder, neuroticism, marital disharmony, and (in women still menstruating) psychological symptoms of the premenstrual syndrome. In the whole sample 16 women (4%) said that they would like help for a sexual problem.The prevalence of sexual dysfunction in this series of women suggests that general practitioners should increase their alertness to the problem in their patients. IntroductionLittle is known about the frequency of sexual dysfunction among women in the general population. In the United States Kinsey et al described the range of sexual behaviour in a large but non-randomly selected sample of women in which those of high educational achievement were overrepresented.' That study was not specifically

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Sexual dysfunction among middle aged women in the community

Osborn¹,

Hawton²,

Gath³

1988

BMJ

197

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“…A statistically significant decrease in serum calcium, phosphorous, and in urinary excretion of calcium during estrogen treatment has been reported (16,34). Our results are in agreement with those studies.…”

Section: Discussionsupporting

confidence: 92%

“…Moore and co-workers reported a decline in serum alkaline phosphatasc activity during estrogen treatment, a result also found in the present study (34). AS alkaline phosphatase as well as the other biochemical parameters studied are indirect indicators of essential metabolic event in bone, the trends favor the assumption of a decreased rate of bone mineral depletion in the estrogen-treated vis-alvis the control group.…”

Section: Discussionsupporting

confidence: 88%

Treatment With Oral Estrone Sulphate in the Female Climacteric

Lagrelius

1981

Acta Obstet Gynecol Scand

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Thirty-eight women were treated with estrone sulphate over a period of 30 months for climacteric problems. A random control group of 29 women were given methyl scopolamine. Bone mineral assays were performed by means of dual photon absorptiometry before the start of treatment and after 6, 12, 18, and 30 months. There was a difference in the mineral loss of trabecular bone between the two groups after 30 months of treatment, that the control group being significantly higher (p less than 0.001). In the estrogen-treated group there was a decrease in serum phosphorus (p less than 0.01), alkaline phosphatase activity (p less than 0.001), and albumin (p less than 0.001). In the control group, serum albumin showed the same decrease, while the other factors either showed no differences or even increased. The urinary excretion of calcium was not significantly reduced in the estrogen group, whereas there was an increase in the control group (p less than 0.01). There was an increase in hematocrit in both groups. Positive correlation was found between parity and loss of trabecular bone mineral (p less than 0.01).U

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“…This syndrome was created unnecessarily in 54 patients who had both healthy ovaries removed at the time of hysterectomy for benign lesions. We would stress the importance of conserving normal ovarian tissue a t hysterectomy and the need for oestrogen replacement in the event of surgical ablation unless strong contraindications to this are present (Moore et al, 1975;Campbell, 1976). The operation may be wholly justified in severe cases, but occasionally an arbitrary age criterion is applied by some surgeons as a prophylactic measure against the possible development of ovarian carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Endocrine Changes and Symptomatology After Oophorectomy in Premenopausal Women

Chakravarti¹,

Collins²,

Newton³

et al. 1977

BJOG

134

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The symptomatic and endocrine changes following hysterectomy and bilateral oophorectomy have been studied in 100 patients, 1 to 31 years after surgery. The most frequent symptoms at the time of interview were depression (62 patients), insomnia (48 patients), loss of libido (46 patients) and dyspareunia (38 patients). Vasomotor symptoms were recorded in 28 patients. Although 94 patients claimed that hot flushes were the first symptomatic changes noticed, 60 had complete relief from these symptoms within 6 months of surgery; 34 patients had no symptoms and only 4 patients were taking oestrogen therapy at the time of interview. Plasma oestradiol and testosterone levels were 78 per cent and 27 per cent respectively below the mean values of day 1 to 10 of the menstrual cycle, similar to those found at comparable years after a normal menopause. The plasma FSH level was about 14 times and the plasma LH level about twice the respective preoperative value. Unlike after the normal menopause, these gonadotrophin levels did not show any decline with increasing age. There was no correlation between plasma hormone levels and the presence of vasomotor symptoms or depression.

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Experience of a National Health Service Menopause Clinic

Cited by 20 publications

References 10 publications

Sexual dysfunction among middle aged women in the community

Sexual dysfunction among middle aged women in the community

Treatment With Oral Estrone Sulphate in the Female Climacteric

Endocrine Changes and Symptomatology After Oophorectomy in Premenopausal Women

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