With the evolution of medical models and diverse healthcare service needs, nurse-led clinics (NLCs) have gained increasing attention. China began experimenting with NLCs in 1997 and their development has accelerated in recent years. This study reviews the current status, management practices, and innovative advancements in NLCs in China and compares them with those in other countries or regions. It analyses the existing challenges and obstacles to the development of NLCs in China, offering valuable insights for promoting their growth. Additionally, this study provides references that can guide the development of NLCs worldwide.