Experience with marginal living related kidney donors: Are they becoming routine or are there still any doubts?

Renal Transplantation - An Experience of 500 Patients

“…Our marginal donor pool of 16% is not unusual as compared to that reported in literature [18,19]. Spousal transplantation accounted for 21.6% of our cases, a figure similar to that reported by many centres in India [20].…”

Recipient Outcomes for Expanded Criteria Living Kidney Donors: The Disconnect Between Current Evidence and Practice

“…The 36 studies were from 13 countries ( (45,54). In some cases, the same donor had multiple expanded criteria (5,31,45 (20)(21)(22)(23)25,26,29,30,36,37,39,40,51,53).…”

“…Three studies did not have any donor controls (i.e. standard criteria donors) (5,28,45). Two studies were conducted in a prospective fashion (40,54), while the remainder were retrospective.…”

Medical Risks in Living Kidney Donors

“…However, studies use varying definitions of "abnormal," and rates vary widely among studies (9 -12,16,17, 19 -21,24,25,42,45,49,50,53). One recent study that included 18 donors with established hypertension found that none had developed proteinuria at a median follow-up of 30 mo (48). However, studies with at least 7 yr of follow-up have shown greater levels of protein excretion in donors with higher BP or established hypertension (9 -11).…”