Experiment study on fracture fixation with low rigidity titanium alloy

Sumitomo, Nozomu; Noritake, Kanako; Hattori, Tomokazu; Morikawa, Keizo; Niwa, Sayaka; Sato, Keiji; Niinomi, Mitsuo

doi:10.1007/s10856-008-3372-y

Cited by 183 publications

(118 citation statements)

References 5 publications

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“…During orthopedic surgery, the use of metallic material with Young's modulus higher than that of the bone can lead to excess bone resorption due to the inhibition of load transfer to the bone (stress shielding effect) [4,5]. Among the different metallic materials, Ti alloys exhibit high strength and relatively low Young's modulus.…”

Section: Low Young's Modulusmentioning

confidence: 99%

Enhancing Functionalities of Metallic Materials by Controlling Phase Stability for Use in Orthopedic Implants

Nakai

Niinomi

Cho

et al. 2015

Interface Oral Health Science 2014

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This chapter aims to review the recent trends pertaining to the enhanced functionalities, including low Young's modulus, self-tunable Young's modulus, and low magnetic susceptibility, of titanium and zirconium alloys for use in orthopedic implants. These value-added functionalities can be realized by controlling the type of crystal structure and their lattice structure stabilities, which are related to the phase stability of titanium and zirconium alloys. Keywords Magnetic susceptibility • Metallic materials • Orthopedic implant • Phase stability • Young's modulus IntroductionOne of the most important factors concerning the use of orthopedic implants is to ensure safety in usage, which is often associated with their mechanical reliability to endure physiologically cyclic loading and unexpected large loads during treatment. Given these considerations, metallic materials are advantageous over ceramic and polymeric materials for use as implantable materials. Therefore, more than 80 % of the implant devices used till date are made of metallic materials [1]. Another important factor concerning the use of orthopedic implants is their toxicity toward living tissues. In general, the human body inherently resists any incoming toxic element. In other words, human body exhibits low permittivity to highly toxic elements eluted from orthopedic implants [2]. That is, the toxicity of orthopedic implants depends not only on the nature of the metallic elements but also on the amount of them, which, in turn, strongly depends on the corrosion resistance of each metallic material. Therefore, in the human body, a metallic material with high corrosion resistance is highly imperative to ensure their safe usage as orthopedic implants.

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Section: Low Young's Modulusmentioning

confidence: 99%

Enhancing Functionalities of Metallic Materials by Controlling Phase Stability for Use in Orthopedic Implants

Nakai

Niinomi

Cho

et al. 2015

Interface Oral Health Science 2014

View full text Add to dashboard Cite

show abstract

“…For example, the Young s moduli of pure Ti and cortical bone are 110 and 10-30 GPa, respectively. As a result of this mismatch, the bone around such metallic implants is insuf ciently loaded, thus causing bone atrophy 1) . This phenomenon, called stress-shielding , has been studied by many researchers.…”

Section: Introductionmentioning

confidence: 99%

Preparation and In Vivo Study of Porous Titanium–Polyglycolide Composite

et al. 2016

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Porous materials show low Young s moduli and excellent bonding to living bone. However, the strength of such materials is often insufcient in the initial stage of implantation. Thus, the objective of this study was to increase the strength of porous titanium by lling the pores with polyglycolide (PGA), a biodegradable plastic. PGA powder was prepared via the thermal decomposition of sodium chloroacetate at 433 K. The PGA was then introduced into the pores of porous Ti (porosity: 60%) using two methods: (i) centrifugal packing and heating and (ii) heat injection. In the latter method, almost all pores were lled by PGA; the lling fraction was measured to be 65-85% regardless of the injection temperature. When the pores in the porous Ti were lled with PGA, the compressive strength increased drastically from 40 to 100 MPa. The increased strength is comparable to that of cortical bone. In addition, the strength increased with increasing injection temperature. In an animal test, unfavourable autopsy ndings, such as suppuration, bleeding, and hyperplasia of the connective tissue, could not be con rmed in rats and no bone was observed in the pores of the Ti-PGA composite. Decomposition of PGA lowered the surrounding pH, it was found to inhibit bone formation in the pores of the porous Ti. It is important to control the decomposition rate of PGA.

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“…The alloys used for implants should have Young's moduli close to those of human bones (around 30 GPa) as this condition minimizes the stress shielding effect [4]. In binary Ti-Nb system, the Young's modulus shows a dependence on Nb content and exhibits two local minima, at about 15 and 42.5 wt% Nb, respectively.…”

Section: Introductionmentioning

confidence: 99%

Evolution of strength and structure during SPD processing of Ti–45Nb alloys: experiments and simulations

et al. 2014

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A b-phase Ti-45Nb alloy was processed by several severe plastic deformation (SPD) methods as highpressure torsion, cold rolling and folding, and hydrostatic extrusion to enhance its strength by achieving an ultrafine grained structure without affecting the Young's modulus being close to that of bone material. Mechanical properties during processing were monitored by direct torque and Vickers hardness measurements, while the micro-/nanostructural evolution was investigated by transmission electron microscopy and X-ray line profile analysis. Simulations of both mechanical and micro-/nano-structural data were performed on the basis of the SPD work-hardening model by Zehetbauer. The simulations not only found a good agreement with the deformation-specific evolution of strength and density of individual dislocations but also well reflected mesoscopic structural quantities such as the sizes of cell/grain interiors and walls without introducing additional fitting parameters.

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Experiment study on fracture fixation with low rigidity titanium alloy

Cited by 183 publications

References 5 publications

Enhancing Functionalities of Metallic Materials by Controlling Phase Stability for Use in Orthopedic Implants

Enhancing Functionalities of Metallic Materials by Controlling Phase Stability for Use in Orthopedic Implants

Preparation and In Vivo Study of Porous Titanium–Polyglycolide Composite

Evolution of strength and structure during SPD processing of Ti–45Nb alloys: experiments and simulations

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