This study presents the energy saving characteristics of the R448A, instead of the R404A refrigeration system, in 5 convenience stores, with a total of 150 m 2 , situated in Central Thailand. The R448A hydrofluorocarbons/hydrofluoroolefins (HFCs/HFOs) (GWP=1390) is a non-azeotropic mixture of R32 (26%), R125 (26%), R1234yf (20%), R134a (21%) and R1234ze (E) (7%), which can be retrofitted to replace the R404A refrigeration system. The R404A hydrofluorocarbons (HFCs) (GWP=3735) is a near azeotropic mixture of R125 (44%), R143A (52%), R134A (4%). Both refrigerants are composed of polyol ester oil (POE), are incombustible and non-toxic. The R448A has a higher cooling capacity (Qe) and lower global warming potentials (GWP) than the R404A due to its hydrofluorocarbons (HFCs) R32 component and hydrofluoroolefins (HFOs) R1234yf/R1234ze (E) component, as opposed to the R404A. This was determined by measuring power consumption (kWh) and the ambient temperature (°C) through the use of power meters and temperature data logger respectively. The result obtained was able to summarize the relationship of all the parameters concerned, and showed an energy-saving average of 7.9%, i.e. 28,273 kWh/year per 5 stores, and a decreased global warming potential (GWP) of 70%, through the use of a digital scroll compressor.