Selective Laser Melting (SLM) is a powder bed layer-by-layer fusion technique mainly applied for additive manufacturing of 3D metallic components of complex geometry. However, the technology is currently limited to printing a single material across each layer. In many applications such as the manufacture of certain aero engine components, conformably cooled dies, medical implants and functional gradient structures, printing of multiple materials are desirable. This paper reports an investigation into the 3D printing of multiple metallic materials including 316L stainless steel, In718 nickel alloy and Cu10Sn copper alloy within a single build-up process using a specially designed multiple material SLM system combining powder-bed with point by point powder dispensing and selective material removal, for the first time. Material delivery system design, multiple material interactions, and component characteristics are described and the associated mechanisms are discussed. 3D printing, selective laser melting, multiple materials 2. Experimental materials and procedure 2.1. Materials Gas atomized spherical 316L stainless steel powder (LPW-718-AACF, 10-45 µm, LPW Technology Ltd., UK), In718 nickel alloy powder (LPW-316-AAHH, 10-45 µm LPW Technology Ltd., UK), Contents lists available at SciVerse ScienceDirect CIRP Annals Manufacturing Technology