The influence of inlet guide vanes on unsteady flow in a centrifugal pump is numerically investigated. The independences of mesh elements, time steps and turbulence models are studied, and the satisfactory agreement between experimental and numerical results of the centrifugal pump performance validates the reliability and accuracy of the numerical model. The frequency characteristics of pressure fluctuations in impeller and volute are nearly the same for the pump without and with inlet guide vanes in the angle range from À36 to þ36 . In the pump impeller, the dominant frequencies are mainly the rotational frequency f i (24.17 Hz) or 2f i , and in volute they are the blade passing frequency f BPF (145 Hz). For the large inlet guide vanes angles of À60 and þ60 , the maximum amplitudes of pressure fluctuations in pump impeller and volute are stronger than that in pump without inlet guide vanes. Therefore, the influence of inlet guide vanes on unsteady flow in the centrifugal pump is slight when the inlet guide vanes angles are regulated in a suitable region.