Experimental and numerical biomechanical analysis of vascular stent

Walke, W.; Paszenda, Z.; Filipiak, Jarosław

doi:10.1016/j.jmatprotec.2005.02.204

Cited by 44 publications

(25 citation statements)

References 10 publications

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“…For the two-dimensional stent implantation simulations, the artery is represented by a 300-mm-thick single layer, modeled as an elastic material with a Poisson's ratio of 0.45 and a Young's modulus of 1 MPa (33). The strut of the stent has a 100 mm Â 100 mm square cross section, which is modeled as an elastoplastic material with a Young's modulus of 270 GPa, a Poisson's ratio of 0.27, a yield strength of 300 MPa, and a tensile strength of 650 MPa, corresponding to 316L stainless steel (34).…”

Section: Simulations Of Stent Deploymentmentioning

confidence: 99%

“…To investigate the typical pressures exerted during stent deployment, we have performed two-dimensional numerical simulations of the deployment of a stent onto an arterial wall. In our simulations, the arterial wall is modeled as a uniform elastic material of equivalent elastic modulus of 1 MPa (33). Fig.…”

Section: The Cell Is Radially Strained In the Vicinity Of The Microinmentioning

confidence: 99%

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Mechanical Criterion for the Rupture of a Cell Membrane under Compression

Gonzalez‐Rodriguez

Guillou

Cornat

et al. 2016

Biophysical Journal

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We investigate the mechanical conditions leading to the rupture of the plasma membrane of an endothelial cell subjected to a local, compressive force. Membrane rupture is induced by tilted microindentation, a technique used to perform mechanical measurements on adherent cells. In this technique, the applied force can be deduced from the measured horizontal displacement of a microindenter's tip, as imaged with an inverted microscope and without the need for optical sensors to measure the microindenter's deflection. We show that plasma membrane rupture of endothelial cells occurs at a well-defined value of the applied compressive stress. As a point of reference, we use numerical simulations to estimate the magnitude of the compressive stresses exerted on endothelial cells during the deployment of a stent.

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Section: Simulations Of Stent Deploymentmentioning

confidence: 99%

Section: The Cell Is Radially Strained In the Vicinity Of The Microinmentioning

confidence: 99%

Mechanical Criterion for the Rupture of a Cell Membrane under Compression

Gonzalez‐Rodriguez

Guillou

Cornat

et al. 2016

Biophysical Journal

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“…Taking into account the duration of the regeneration process of the individual layers of a vessel wall after their mechanical injury [29][30][31] e.g. as a result of angioplasty, we can conclude that the time needed for partial regeneration of the arterial wall is approx.…”

Section: Discussionmentioning

confidence: 99%

Mechanical, rheological, fatigue, and degradation behavior of PLLA, PGLA and PDGLA as materials for vascular implants

et al. 2012

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The biggest challenge in the treatment of arterial stenosis remains the issue of optimization of stent design. Despite continuous improvement in surgical techniques and use of intensive pharmacotherapy, the results of stent coronary interventions may be unsatisfactory, and long-term interaction of a metal implant with a blood vessel results in complications such as recurrent stenosis and thrombosis. Therefore, it is necessary to search for new materials and stent designs to obtain a stent capable of restoring flow in the vessel and disappearing after fulfilling its function. Such stent must also be compatible with the vessel wall to enable regeneration of new structure of endothelium and deeper artery layers damaged during implantation. Consequently, there is ongoing search for functional solutions with minimum effects of long-term implant-tissue interaction. In light of the above, the team investigated the possibility of using biodegradable polymers already mentioned in the literature as a construction material for vascular stent. The study used three polyhydroxyacids based on lactic acid and glycolic acid: poly(l-lactide), poly(lactideco-glycolide) and poly(d,l-lactide-co-glycolide). The research focused on assessing changes in mechanical, thermomechanical, rheological, and fatigue properties during the process of hydrolytic degradation. The analysis also covered the rate of release of degradation products. The results of the conducted tests indicate the possibility of developing a vascular stent with biodegradable polymers.

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“…The balloon-expandable stent socalled Palmaz-Schatz stent was analyzed for elaboration of the computational model [3], which is useful for finding the biomechanical response to changes of geometric parameters like: implantation pressure, dogboning, foreshortening, stresses and strain distribution in the stent. It is an important in terms of the effectiveness of the surgical procedure 1.…”

Section: Introductionmentioning

confidence: 99%

Optimization of dogboning phenomenon of the coronary artery stent

Ciekot¹,

Idziak-Jabłońska²,

Lacki³

2012

Sci. Res. Inst. Math. Comp. Sci.

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Abstract. Optimization of the dogboning phenomenon of the coronary artery stent is the aim of the paper. The mathematical model for the slotted tube stent is formulated with the finite element analysis based on a parametric geometric model of stent. Some of the mechanical properties are examined: the expanding pressure, plastic strain, foreshortening and dogboning. This paper is focused on determination of the optimal parameters for lowest dogboning.

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Experimental and numerical biomechanical analysis of vascular stent

Cited by 44 publications

References 10 publications

Mechanical Criterion for the Rupture of a Cell Membrane under Compression

Mechanical Criterion for the Rupture of a Cell Membrane under Compression

Mechanical, rheological, fatigue, and degradation behavior of PLLA, PGLA and PDGLA as materials for vascular implants

Optimization of dogboning phenomenon of the coronary artery stent

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