Experimental and Numerical Investigation of Spray-Drying Parameters on the Dried Powder Properties of<i>Ginkgo biloba</i>Seeds

Zhang, Cai Hong; Huang, Li Xin; Wang, Chun Peng; Mujumdar, Arun S.

doi:10.1080/07373931003645033

Cited by 18 publications

(10 citation statements)

References 19 publications

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“…[5] Several techniques can be applied for this goal, such as freeze drying, [6][7][8] spouted bed drying, [9,10] fluidized bed drying, [11][12][13][14] and spray drying. [4,[15][16][17][18][19][20][21][22][23] Spray drying is probably the most common technique used in the phytopharmaceutical industries, [5,17,19] mostly due to the several advantages presented by this technology, such as operational flexibility, [23] an applicability for heat-sensitive materials, [24][25][26][27][28] as well as an affordable cost. [23] Furthermore, spray-dried powders may be engineered with optimized characteristics, such as a high stability and an ease of handling, transportation, and storage.…”

Section: Introductionmentioning

confidence: 99%

Development of a Phytopharmaceutical Intermediate Product via Spray Drying

et al. 2011

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The influence of concentration and incorporation time of different drying excipients on the processing yields and physical properties of Eugenia dysenterica DC spray-dried extracts were investigated following a factorial design. Under the established conditions, the process yield ranged from 57.55 to 89.14%, and in most experiments, the recovered products presented suitable flowability and compressibility, as demonstrated by the Hausner factor, Carr index, and angle of repose. Additionally, in a general way, the parameters related to the dried products' flowability varied over a range acceptable for pharmaceutical purposes. An analysis of variance (ANOVA) proved that both factors and some of their interactions significantly affected most of the investigated responses at different levels. Mannitol proved to be an interesting alternative as an excipient for the drying of herbal extracts, even at low concentrations such as 12.5%. Furthermore, these results imply that the best condition to obtain dry extracts of E. dysenterica with high performance and adequate pharmacotechnical properties involves the lowest concentration and the highest incorporation time of mannitol.

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Section: Introductionmentioning

confidence: 99%

Development of a Phytopharmaceutical Intermediate Product via Spray Drying

et al. 2011

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“…In this context, among studied species can be related Rhamnus purshiana (Gallo et al, 2011), Phyllanthus niruri (Couto, 2005), Achyrocline satureioides (Petrovick, 2006) and Ginkgo biloba (Zhang et al, 2010), which have been used as active raw material in the production of dried plant extracts. However, the successful development of these products, i.e.…”

Section: Introductionmentioning

confidence: 99%

Influence of process conditions on the physicochemical characteristics of cumaru (Amburana cearensis) powder produced by spray drying

Araruna¹,

Silva²,

Canuto³

et al. 2013

Rev. bras. farmacogn.

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Abstract:The aim of the work was to study the spray-drying of ethanolic extract from Amburana cearensis (Allemão) A.C. Sm., Fabaceae, in order to obtain powders with better pharmacological and technological properties for herbal medicine. A 2 3 fractional factorial statistical design was used to find adequate spray-drying operating conditions (inlet air temperature; feed flow rate and air flow rate) to produce A. cearensis powder with adequate concentration of active principles (amburoside and coumarin), low moisture content and high process yield. The HPLC analyses showed that the spray-drying powder of A. cearensis production did not cause alterations in the chromatographic profile when related to the fluid extract. The most significant factor that affected the amburoside concentration was air flow rate, while the concentration of coumarin, a thermolabile molecule, was influenced mainly by inlet air temperature. The moisture content of the spray-drying powder of A. cearensis varied from 3.72 to 5.85% (w/w), while the maximal process yield was 41.1% (w/w). The present study demonstrates for the first time the best operating conditions to produce A. cearensis extract powder that were adequate when related to the coumarin and amburoside concentrations and moisture content. However, additional studies are still needed to improve mainly it technological characteristics.

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“…Tomates com pré-tratamento osmótico, avaliados por Camargo (2005) apresentaram resultados maiores de atividade de água (Aw=0,86), quando comparados ao obtido neste experimento, em função das características do material, condições de processos e equipamentos utilizados que podem interferir nos resultados (CHANG et al, 2006). A atividade de água é um dos fatores mais importantes para a estabilidade microbiológica de produtos desidratados (FENNEMA, 1993;JANGAM;THORAT, 2010;ZHANG et al, 2010 Nota: Valores médios; Desvio padrão. DASDO= Desidratação adiabática sem pré-tratamento osmótico, DACDO= Desidratação adiabática com pré-tratamento osmótico, LSDO= Liofilização sem pré-tratamento osmótico, LCDO= Liofilização com pré-tratamento osmótico.…”

Section: Efeito Das Aplicações De Antioxidante E Acidulanteunclassified

Variáveis relacionadas ao processamento de minitomates inteiros desidratados em secador convectivo adiabático e liofilizados

Correia¹

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Experimental and Numerical Investigation of Spray-Drying Parameters on the Dried Powder Properties ofGinkgo bilobaSeeds

Cited by 18 publications

References 19 publications

Development of a Phytopharmaceutical Intermediate Product via Spray Drying

Development of a Phytopharmaceutical Intermediate Product via Spray Drying

Influence of process conditions on the physicochemical characteristics of cumaru (Amburana cearensis) powder produced by spray drying

Variáveis relacionadas ao processamento de minitomates inteiros desidratados em secador convectivo adiabático e liofilizados

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