Experimental and numerical studies of two arterial wall delamination modes

Leng, Xiaochang; Zhou, Boran; Deng, Xiaomin; Davis, Lindsey A.; Lessner, Susan M.; Sutton, Michael A.; Shazly, Tarek

doi:10.1016/j.jmbbm.2017.09.025

Cited by 21 publications

(29 citation statements)

References 23 publications

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“…Ferrara and Pandolfi (2010) applied a cohesive zone model (CZM) together with an anisotropic traction-separation law and investigated one of the peel tests conducted by Sommer et al (2008). In an experimental and computational study, Leng et al (2018) employed the CZM to fit the model parameters to load-displacement curves obtained from a shear dominated mixed-mode and a mode I peel test along both circumferential and longitudinal directions. Apart from that, Noble et al (2017) carried out experimental and computational analyses of a catheter-induced delamination.…”

Section: Introductionmentioning

confidence: 99%

Computational modeling of progressive damage and rupture in fibrous biological tissues: application to aortic dissection

Gültekin

Hager

Dal

et al. 2019

Biomech Model Mechanobiol

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Section: Introductionmentioning

confidence: 99%

Computational modeling of progressive damage and rupture in fibrous biological tissues: application to aortic dissection

Gültekin

Hager

Dal

et al. 2019

Biomech Model Mechanobiol

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“…Thus, the cerebral arterial wall was modeled as Holzapfel–Gasser–Ogden (HGO) [ 20 ] material model, which was used to capture the bulk arterial material behavior. Due to the limited HGO parameter values for cerebral artery, a set of parameter values from carotid arterial wall or abdominal arterial wall were adopted, which the parameters were chosen as μ = 3.82e−3 MPa, k 1 = 0.996 MPa, k 2 = 524, κ = 0.226 and the collagen fibers angle is 49.9 [ 20 – 23 ]. The aneurysm vessel wall was model as membrane element with a thickness of 0.3 mm [ 24 ].…”

Section: Methodsmentioning

confidence: 99%

Numerical simulation of patient-specific endovascular stenting and coiling for intracranial aneurysm surgical planning

Leng¹,

Wang

et al. 2018

J Transl Med

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BackgroundIn this study, we develop reliable and practical virtual coiling and stenting methods for intracranial aneurysm surgical planning. Since the purpose of deploying coils and stents is to provide device geometries for subsequent accurate post-treatment computational fluid dynamics analysis, we do not need to accurately capture all the details such as the stress and force distribution for the devices and vessel walls. Our philosophy for developing these methods is to balance accuracy and practicality.MethodsWe consider the mechanical properties of the devices and recapitulate the clinical practice using a finite element method (FEM) approach. At the same time, we apply some simplifications for FEM modeling to make our methods efficient. For the virtual coiling, the coils are modeled as 3D Euler–Bernoulli beam elements, which is computationally efficient and provides good geometry representation. During the stent deployment process, the stent–catheter system is transformed according to the centerline of the parent vessel since the final configuration of the stent is not dependent of the deployment history. The aneurysm and vessel walls are assumed to be rigid and are fully constrained during the simulation. All stent–catheter system and coil–catheter system are prepared and packaged as a library which contains all types of stents, coils and catheters, which improves the efficiency of surgical planning process.ResultsThe stent was delivered to the suitable position during the clinical treatment, achieving good expansion and apposition of the stent to the arterial wall. The coil was deployed into the aneurysm sac and deformed to different shapes because of the stored strain energy during coil package process and the direction of the microcatheter.ConclusionsThe method which we develop here could become surgical planning for intracranial aneurysm treatment in the clinical workflow.

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“…In this study, specimens were made of diseased media (DM) and fibrous cap (FC) obtained from human carotid artery after endarterectomies. The experimental setup is similar to the uniaxial tensile tests of porcine abdominal aortas [9, 10]. The diseased media and fibrous cap were isolated, washed in PBS and dissected from the perivascular tissue.…”

Section: Methodsmentioning

confidence: 99%

Determination of Viscoelastic Properties of human Carotid Atherosclerotic Plaque by Inverse Boundary Value Analysis

Leng

Zhou

Deng

et al. 2018

IOP Conf. Ser.: Mater. Sci. Eng.

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Abstract. In this study, we assessed the mechanical response of samples from human atherosclerotic diseased media and fibrous cap via uniaxial tensile testing. Results show a pronounced hysteresis phenomenon caused by viscoelasticity during the loading-unloading process. An inverse analysis method with finite element modeling was employed to identify the material parameter values for a viscoelastic anisotropic (VA) constitutive model through matching simulation predictions of load-displacement curves with experimental measurements. The identified material parameter values can be used in simulation studies of diseased human carotid arteries, including investigations of inflation processes associated with stenting or angioplasty.

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Experimental and numerical studies of two arterial wall delamination modes

Cited by 21 publications

References 23 publications

Computational modeling of progressive damage and rupture in fibrous biological tissues: application to aortic dissection

Computational modeling of progressive damage and rupture in fibrous biological tissues: application to aortic dissection

Numerical simulation of patient-specific endovascular stenting and coiling for intracranial aneurysm surgical planning

Determination of Viscoelastic Properties of human Carotid Atherosclerotic Plaque by Inverse Boundary Value Analysis

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