Lightweight modular structures have become a requirement in today’s world, especially for areas that are prone to occurrence of extreme events, such as earthquakes and blasts, and are situated in difficult terrains with challenging accessibility. Sandwiched composites can be one of the most suitable building units for construction of these structures due to their engineered mechanical and physical properties. Therefore, in this numerical study, performance assessment of a sandwich modular structure in the shape of a truncated cylinder is conducted under blast load. The sandwich modular structure is composed of flat and curved carbon fiber-reinforced polymer (CFRP) and extruded polystyrene (XPS) foam sandwich panels. A three-dimensional (3D) finite element (FE) model of the sandwich modular structure is developed considering the orthotropic behavior of CFRP facesheets and the crushing foam behavior is accounted for the XPS foam core in the FE modeling. The damage assessment in the CFRP facesheet is performed using Hashin’s damage criterion. Furthermore, the effect of polyurea with varying thicknesses on the blast-resistance of the structure is investigated. The polyurea is modeled as hyperelastic material using the Mooney-Rivlin model. The influence of polyurea positioning is studied when (a) applied externally to flat and curved walls of the structure directly exposed to the blast and (b) applied internally to flat and curved walls of the structure opposite to the exposure of the blast (rear face). It is observed that the flat walls of the structure are more vulnerable to the blast load than the curved walls of the structure. Moreover, a quadratic and linear reduction in the deflection of flat and curved walls with increasing thickness of polyurea coating is obtained, respectively. In addition, with increasing thickness of the additional polyurea coating, a logarithmic reduction in the kinetic energy of the sandwich modular structure is reported.