Experimental and theoretical analysis of shear–force interaction in the non-contact regime with 100 pN force resolution

Schmidt, Jochen; Bergander, H.; Eng, Lukas M.

doi:10.1016/s0169-4332(99)00542-5

Cited by 9 publications

(5 citation statements)

References 14 publications

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“…15,16 The mechanical properties of the tragal cartilage were obtained in the literature according to Wen et al 17 The material of the TORP is characterized as being titanium grade 2. The glue properties were obtained in the literature according to Schimidt et al 18 For the prosthesis, the Poisson ratio is 0.37 and for the glue is 0.4. The contacts between the geometrical models were of type-TIE and hard contact.…”

Section: Femmentioning

confidence: 99%

Total Ossicular Replacement Prosthesis of the Middle Ear: A Biomechanical Analysis

Gentil¹,

Marques

Parente

et al. 2015

J. Mech. Med. Biol.

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The main goal of the present study is to analyze and characterize the behavior of the middle ear, when a total ossicular replacement prosthesis (TORP) is used in the ossicular chain, in order to troubleshoot conductive hearing loss. Using a finite element model (FEM), a dynamic study of the middle ear was made. The displacement values were obtained at the umbo and stapes footplate, for a sound pressure level of 80 dB sound pressure level (SPL) applied at the tympanic membrane, when a cartilage in membrane-prosthesis interface of different diameters and thicknesses was used. The results were compared with the healthy middle ear model. The usage of this model aims to achieve a set of techniques that promotes the best possible performance of prosthesis in the middle ear. The present study allows to conclude that the rehabilitation of the middle ear with TORP can lead to the best results when used with 4 mm diameter cartilages, with a thin thickness of 0.3 mm.

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Section: Femmentioning

confidence: 99%

Total Ossicular Replacement Prosthesis of the Middle Ear: A Biomechanical Analysis

Gentil¹,

Marques

Parente

et al. 2015

J. Mech. Med. Biol.

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“…There are different theories concerning the origin of the forces, i.e. viscosity, elasticity, adhesive, capillary, electrostatic or even repulsive (knocking and friction), and a number of experiments have been performed in order to investigate this issue [11][12][13][14][15][16][17][18][19]. Nevertheless, from the practical point of view, regardless of the origin of the phenomena, one can perform the approach curve measurement, which can deliver information about tip-sample distance.…”

Section: The Tip-sample Distancementioning

confidence: 99%

“…When the tip-sample distance is estimated ('h' factor used in equations presented below), one can calculate the deviation value. It must be emphasized that tip-sample distance estimation is still considerably difficult due to a problem with defining the permanent contact point (0 nm distance), and has been discussed in several papers [13,17]. Mostly the '0' oscillation amplitude is recognized as the '0' tip-sample distance.…”

Section: The Tip-sample Distancementioning

confidence: 99%

Correction of structure width measurements performed with a combined shear-force/tunnelling microscope

Sikora¹

2007

Meas. Sci. Technol.

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Atomic force microscopy is one of the most precise and reliable methods for both the creation and the investigation of nanostructures. In order to obtain reliable measurement one must be aware of the specific issues of the method. Non-contact AFM is a particular case, where due to complex tip–sample interaction, specific measurement consideration is necessary. In this paper an analysis of sample surface misshape phenomena in shear-force microscopy is carried out and a method for the estimation of a correction to the lateral size of nanostructures is presented. Some practical examples of the application of this method are given, accompanied by additional investigations with a newly developed combined shear-force/tunnelling microscope, which allows taking a closer look at these phenomena.

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“…There has been significant interest in mass-sensitive biosensors derived from Quartz Tuning Forks (QTFs) for biomedical applications in recent years, primarily due to the high-quality factor (10 3 -10 5 ), the cost-effective fabrication, the low energy consumption, and the inherent stability of these devices. The use of QTFs has proven useful for a variety of applications, including time-frequency standard systems, atomic force microscopy, gas and humidity sensing, quartz-enhanced photoacoustic spectroscopy (QEPAS), and, more recently, biosensing investigations [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. The technique relies on the detection of biomolecules within gaseous or liquid media, whereby the mass of the target analytes is converted into a measurable signal, known as the resonant frequency (f).…”

Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Chitosan Modified Quartz Tuning Fork Sensors for Real Time Biosensing in Liquid Environment

KALELİ CAN

2024

Düzce Üniversitesi Bilim Ve Teknoloji Dergisi

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Several new sensing technologies have emerged to meet the escalating demand for accurate and rapid diagnosis. We present an overview of the development of highly sensitive and selective Quartz Tuning Fork (QTF)-based sensors in a liquid environment, which will be critically important for contemporary diagnostic methods reliant on sensing technologies. The purpose of this study is to modify QTF prongs using molecularly imprinted chitosan, in combination with the operation of a quartz tuning fork as a piezoelectric crystal for biomedical applications. Through real-time data acquisition, we evaluate QTF resonance frequency shifts in dry and liquid environments using a model protein, BSA. As a result, the QTF-based sensor fails to detect BSA in dry conditions. It is however possible to measure frequency shifts ranging from 5 to 25 µg /mL within a liquid matrix. There is a rapid equilibration response time of 2 to 10 minutes depending on the concentration of BSA in the sensor. With the developed QTF-based sensor, a sensitivity of 1.1069 Hz/ µg has been achieved within the liquid matrix. As a result of the excellent properties of molecularly imprinted chitosan, it has been possible to develop a QTF-based biosensor capable of acquiring real-time data even when it is in liquid solutions.

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Experimental and theoretical analysis of shear–force interaction in the non-contact regime with 100 pN force resolution

Cited by 9 publications

References 14 publications

Total Ossicular Replacement Prosthesis of the Middle Ear: A Biomechanical Analysis

Total Ossicular Replacement Prosthesis of the Middle Ear: A Biomechanical Analysis

Correction of structure width measurements performed with a combined shear-force/tunnelling microscope

Molecularly Imprinted Chitosan Modified Quartz Tuning Fork Sensors for Real Time Biosensing in Liquid Environment

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