Experimental and theoretical investigation for surface plasmon resonance biosensor based on graphene/Au film/D-POF

Gong, Weiliang; Jiang, Shouzhen; Li, Zhen; Li, Chonghui; Xu, Jihua; Pan, Jie; Huo, Yanyan; Man, Baoyuan; Liu, Aihua; Zhang, Chao

doi:10.1364/oe.27.003483

Cited by 62 publications

(21 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As shown in Figure 10a, the variations of absorption spectrum to 100 nM FC-DNA was taken as an example, which was shown in Figure 10b (the black curve) that presented the wavelength shift as a function of hybridization time. When the target DNA molecules were continuously captured by modified probe DNA, the RI around the sensing surface would increase [38]. Obviously, the sensor had an intense response to FC-DNA hybridization before 50 min, and then the response was gradually stabilized.…”

Section: Resultsmentioning

confidence: 99%

Preparation of Graphene/ITO Nanorod Metamaterial/U-Bent-Annealing Fiber Sensor and DNA Biomolecule Detection

Yang

et al. 2019

Nanomaterials

Self Cite

View full text Add to dashboard Cite

In this paper, a graphene/ITO nanorod metamaterial/U-bent-annealing (Gr/ITO-NM/U-bent-A)-based U-bent optical fiber local surface plasmon resonance (LSPR) sensor is presented and demonstrated for DNA detection. The proposed sensor, compared with other conventional sensors, exhibits higher sensitivity, lower cost, as well as better biological affinity and oxidize resistance. Besides, it has a structure of an original Indium Tin Oxides (ITO) nanocolumn array coated with graphene, allowing the sensor to exert significant bulk plasmon resonance effect. Moreover, for its discontinuous structure, a larger specific surface area is created to accommodate more biomolecules, thus maximizing the biological properties. The fabricated sensors exhibit great performance (690.7 nm/RIU) in alcohol solution testing. Furthermore, it also exhibits an excellent linear response (R2 = 0.998) to the target DNA with respective concentrations from 0.1 to 100 nM suggesting the promising medical applications of such sensors.

show abstract

Section: Resultsmentioning

confidence: 99%

Preparation of Graphene/ITO Nanorod Metamaterial/U-Bent-Annealing Fiber Sensor and DNA Biomolecule Detection

Yang

et al. 2019

Nanomaterials

Self Cite

View full text Add to dashboard Cite

show abstract

“…This strategy based on covalently bonding antibodies on the graphene surface provided a very low LOD of 1 pM. Other approaches have been reported to improve the sensitivity of SPR for DNA hybridization analysis ( W. Gong et al, 2019 ).…”

Section: Graphene-based Materials In Virus Sensingmentioning

confidence: 99%

Human virus detection with graphene-based materials

Vermisoglou

Panáček

Jayaramulu

et al. 2020

Biosensors and Bioelectronics

163

117

View full text Add to dashboard Cite

Our recent experience of the COVID-19 pandemic has highlighted the importance of easy-to-use, quick, cheap, sensitive and selective detection of virus pathogens for the efficient monitoring and treatment of virus diseases. Early detection of viruses provides essential information about possible efficient and targeted treatments, prolongs the therapeutic window and hence reduces morbidity. Graphene is a lightweight, chemically stable and conductive material that can be successfully utilized for the detection of various virus strains. The sensitivity and selectivity of graphene can be enhanced by its functionalization or combination with other materials. Introducing suitable functional groups and/or counterparts in the hybrid structure enables tuning of the optical and electrical properties, which is particularly attractive for rapid and easy-to-use virus detection. In this review, we cover all the different types of graphene-based sensors available for virus detection, including, e.g., photoluminescence and colorimetric sensors, and surface plasmon resonance biosensors. Various strategies of electrochemical detection of viruses based on, e.g., DNA hybridization or antigen-antibody interactions, are also discussed. We summarize the current state-of-the-art applications of graphene-based systems for sensing a variety of viruses, e.g., SARS-CoV-2, influenza, dengue fever, hepatitis C virus, HIV, rotavirus and Zika virus. General principles, mechanisms of action, advantages and drawbacks are presented to provide useful information for the further development and construction of advanced virus biosensors. We highlight that the unique and tunable physicochemical properties of graphene-based nanomaterials make them ideal candidates for engineering and miniaturization of biosensors.

show abstract

“…However, these sensors require complex manufacturing processes, expensive equipments and hence high production cost. Because of its superior performance, optical coupling, machinability, robustness and handling of plastic optical fibers (POF) have received tremendous attention in the recent past [9][10][11][12][13]. For the improvement in refractive index sensitivity of POFs, various kinds of structural modifications have been employed in tapering mode fibers, making hole in fibers and side polishing of fibers, etc.…”

Section: Introductionmentioning

confidence: 99%

Comprehensive Study and Experimental Validation of U-shaped Probe Extrinsic Fiber Optic Sensor for the Measurement of Refractive Index at Various Temperatures using a Tunable Light Source

Rao¹

2021

ITII

View full text Add to dashboard Cite

Extensive detection performances due to sensitivity to external and internal perturbations in the fiber structure makes the optical fiber sensors highly superior over the conventional sensors. The fiber optic sensors with clad removed fibers at some portion along its length play a vital role in the determination of refractive index of various liquids at several wavelengths and at several temperatures. In the present paper a refractive index sensor has been developed to investigate the performance and experimental validation in the measurement of R.I. values of liquids at various temperatures using a tunable light source capable of emitting light at the wavelengths of 630nm, 660nm, 820nm and 850nm. The U-shaped glass probe connected between the tunable light source and an optical detector using two multimode PCS fibers of 200/230μm, acts as a clad removed portion of the sensor which is called as sensing zone or sensing region. In the working principle of the sensor, the U-shaped glass rod immersed into each mixture prepared with the combination of Toluene and Acetonitrile, the light launched from the source reaching the detector was noted at various temperatures and by tuning the wavelength of the source to 630nm, 660nm, 820nm and 850nm. From the data obtained, the sensor was calibrated to measure the refractive index of various liquids at different temperatures and wavelengths. Exploiting all the advantages offered by the fiber optic communication systems, the sensor was expected to be rugged, robust, reliable, and durable offering the sensitivity in the range of the order of 10-5.

show abstract

Experimental and theoretical investigation for surface plasmon resonance biosensor based on graphene/Au film/D-POF

Cited by 62 publications

References 42 publications

Preparation of Graphene/ITO Nanorod Metamaterial/U-Bent-Annealing Fiber Sensor and DNA Biomolecule Detection

Preparation of Graphene/ITO Nanorod Metamaterial/U-Bent-Annealing Fiber Sensor and DNA Biomolecule Detection

Human virus detection with graphene-based materials

Comprehensive Study and Experimental Validation of U-shaped Probe Extrinsic Fiber Optic Sensor for the Measurement of Refractive Index at Various Temperatures using a Tunable Light Source

Contact Info

Product

Resources

About