Experimental atherosclerosis and hyperlipidemia in rats and rabbits: Influence of some alimentary fats

Effect of atherogenic diets deficient in vitamin B12, choline, and protein of physiological parameters of the rat

“…The formation of cephalin, a phospho lipid which does not contain choline, could have taken place.Since analyses for the different types of phospholipids were not conducted, it is impossible to determine the exact mechanism.Total esterified fatty acidsWith the sexes combined, the whole-plot total esterified fatty acid values for the basal, cholesterol and cholesterol plus hydrogenated coconut oil supplementation are 541.2, 568.9 and 572.0 mg/lOOml, respectively (Figure 6). The observed responses were not significant which are similar to those reported byLibert and Rogg-Effront (1962).gure 6 Total plasma esterified fatty acids (mg/lOOml) the whole-plot and split-plot treatments with sexes…”

“…Kinsell and Micheals (1955) reported that human serum cholesterol and phospholipid values consistently decreased when vegetable oils replaced the animal fat. Libert and Rogg-Effront (1962) demonstrated after four months on an "inductive diet" containing choles terol, sodium cholate and propylthiouracil that no signifi cant differences in total serum esterified fatty acids or serum cholesterol occurred with rats fed peanut meal, lard, margarine or corn oil. Moore and Williams (1964b) showed viith rabbits that hydrogenated coconut oil elevated the lipid plasma fractions four to five times greater than the values obtained by supplementation with other fats.…”