This paper presents the results of experiments on the study of a hydraulic fracture’s interaction with a preexisting fracture. A distinctive feature of the conducted experiments is the ability to use ultrasonic transmitting monitoring to measure the fracture propagation and opening simultaneously with the pore pressure measurements at several points of the porous saturated sample. It allows us to obtain the pressure distributions at various experiment stages and to establish a relation between the pore pressure distribution and hydraulic fracture propagation and its interaction with macroscopic natural fractures. The possibilities of active ultrasonic monitoring have been expanded due to preliminary calibration experiments, which make it possible to estimate the fracture opening via attenuation of ultrasonic pulses. The experiment demonstrated the most complex scenario of fracture interactions when a hydraulic fracture intersected with a natural fracture and the natural fracture in the vicinity of the intersection was also opened. The additional complications arise from fracture arrangement: the hydrofracture was normal with respect to the base plane, while the natural fracture was slanted. This led to gradual growth of the intersection zone as the hydrofracture propagated. The experiments show that the natural fracture limited the fracture’s propagation. This was caused by the hydraulic fracturing fluid leaking into the natural fracture; thus, both the hydraulic fracture and natural fracture compose a united hydraulic system.