Experimental design and capillary electrophoresis for simultaneous analysis of arbutin, kojic acid and hydroquinone in cosmetics

Lin, Yen-Hwei; Yang, Yi‐Hsin; Wu, Shou‐Mei

doi:10.1016/j.jpba.2007.02.004

Cited by 81 publications

(24 citation statements)

References 18 publications

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“…Thus, from the equations, J = 1.12 × 10 –14 cm 3 ·L·mol –1 , E = 0.073, R 0 = 1.77 nm, and r = 3.26 nm were obtained. The binding distance r is less than 7 nm, which indicates that the energy transfer occurs between BSA and FSD with high probability .…”

Section: Resultsmentioning

confidence: 99%

Interaction between fasudil hydrochloride and bovine serum albumin: spectroscopic study

Jiang

Xun

et al. 2015

Luminescence

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The interaction between fasudil hydrochloride (FSD) and bovine serum albumin (BSA) was investigated using fluorescence and ultraviolet spectroscopy under imitated physiological conditions. The Stern-Volmer quenching model has been successfully applied and the results revealed that FSD could quench the intrinsic fluorescence of BSA effectively via static quenching. The binding constants and binding sites for the BSA-FSD system were evaluated. The corresponding thermodynamic parameters obtained at different temperatures indicated that hydrophobic force played a major role in the interaction of FSD and BSA. The distance between the donor (BSA) and the acceptor (FSD) was obtained according to fluorescence resonance energy transfer (FRET). Synchronous fluorescence spectroscopy and FT-IR spectra showed that the conformation of BSA was changed in the presence of FSD. Copyright © 2015 John Wiley & Sons, Ltd.

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Section: Resultsmentioning

confidence: 99%

Interaction between fasudil hydrochloride and bovine serum albumin: spectroscopic study

Jiang

Xun

et al. 2015

Luminescence

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“…Arbutin may release hydroquinone following in vivo cleavage of the glycosidic bonds or via hydrolysis by human skin bacteria [13]. Several analytical methods have been reported for the quantitative determination of arbutin in cosmetics using high-performance liquid chromatography (HPLC) [6,[14][15][16][17][18], microdialysis sampling coupled to HPLC [19] and HPLC with chemiluminescence detection [20], gas chromatography/mass spectrometry [21], micellar electrokinetic capillary chromatography (MEKC) [22], MEKC with amperometric detection [23], and online derivatization followed by disposable electrochemical sensing [24]. Moreover, hydroquinone has been analysed in cosmetic creams and topical dermatologic drugs using HPLC [16,[25][26][27], capillary electrochromatography [28], MEKC [22,29], spectrophotometry [30], thin layer chromatography [31] and biomimetic sensor technology [32].…”

Section: Synopsismentioning

confidence: 99%

Simultaneous determination of arbutin and its decomposed product hydroquinone in whitening creams using high‐performance liquid chromatography with photodiode array detection: Effect of temperature and pH on decomposition

Jeon

Kim

Lee

et al. 2015

Intern J of Cosmetic Sci

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“…Previous studies have employed analytical methods such as thin layer chromatography [4], micellar liquid chromatography [5], capillary electrophoresis [6,7], high-performance liquid chromatography (HPLC) [8][9][10], liquid chromatography-mass spectrometry (LC-MS) [11,12], and gas chromatography-mass spectrometry (GC-MS) [13][14][15] for screening and determining arbutin. Recently, mass spectrometry-based approaches have been increasingly employed for the determination of arbutin due to their high selectivity and sensitivity.…”

Section: Introductionmentioning

confidence: 99%

Determination and quantification of arbutin in plants using stable isotope dilution liquid chromatography–mass spectrometry

Kim

Park

et al. 2018

Appl Biol Chem

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Arbutin is a very safe whitening agent for human skin. Since it is more expensive than other agents and has a challenging synthesis, novel methods to obtain this valuable agent are needed. In this study, we developed a precise and accurate method to detect and quantify arbutin using stable isotope dilution liquid chromatography-mass spectrometry (LC-MS). One challenge that needed to be overcome was the matrix effect occurring during the LC-MS analysis due to the analyte ionisation enhancement or suppression in the electrospray ionisation source by coeluting compounds. Notably, arbutin had different matrix effects in the various sample matrices. A solution to this problem was the use of [d 4 ]-arbutin as a stable isotopelabelled internal standard (SIL-IS), as it compensated the matrix effect of arbutin because it was affected by almost the same matrix effect. The validation of the developed method showed excellent linearity (r 2 = 1.000), precision (relative standard deviation B 2.5%), accuracy (recovery, 97.42-98.52%), limit of detection (0.03 lg/mL), and limit of quantification (0.1 lg/mL). Finally, the method of arbutin detection was applied to blueberry leaves to compare the precision and accuracy results obtained by performing stable isotope dilution using LC-MS and gas chromatography-mass spectrometry. The method was applied to strawberry leaves and pear peels, indicating that the SIL-IS method can be expected to find application in the arbutin analysis in other plants.

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Experimental design and capillary electrophoresis for simultaneous analysis of arbutin, kojic acid and hydroquinone in cosmetics

Cited by 81 publications

References 18 publications

Interaction between fasudil hydrochloride and bovine serum albumin: spectroscopic study

Interaction between fasudil hydrochloride and bovine serum albumin: spectroscopic study

Simultaneous determination of arbutin and its decomposed product hydroquinone in whitening creams using high‐performance liquid chromatography with photodiode array detection: Effect of temperature and pH on decomposition

Determination and quantification of arbutin in plants using stable isotope dilution liquid chromatography–mass spectrometry

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