Experimental design for study of cardiopulmonary resuscitation in dogs

Barsan, William G.; Levy, Richard

doi:10.1016/s0196-0644(81)80377-0

Cited by 59 publications

(27 citation statements)

References 12 publications

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“…The ECMO pump can immediately generate sufficient blood flow in adult patients after cannulation of the artificial circuit, while conventional chest compression results in a cardiac output of only 25%–30% of normal, even when performed under optimal conditions 13. Thus, rapid ECMO initiation in refractory cardiac arrest supports organ, cerebral and myocardial perfusion, oxygenation and improves metabolic state after circulatory arrest 14.…”

Section: Discussionmentioning

confidence: 99%

Clinical outcomes after rescue extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest

Yang

Cho

et al. 2016

Emerg Med J

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Section: Discussionmentioning

confidence: 99%

Clinical outcomes after rescue extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest

Yang

Cho

et al. 2016

Emerg Med J

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“…[1][2][3][4][5] Cardiac output generated by CPR is 17-27% of that under normal conditions. [6][7][8][9] For the improvement of the haemodynamic effect, many researchers have tried to find the optimal depth, rate of chest compression, and the ideal compression-ventilation ratio. 10,11 However, there were only a few studies related with the optimal position of hands during chest compression.…”

Section: Introductionmentioning

confidence: 99%

Estimation of anatomical structures underneath the chest compression landmarks in children by using computed tomography

Park

Kim

et al. 2011

Resuscitation

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“…It was pointed out that extension of CPR duration and usage of high-dose inotropic treatment was associated with increased mortality (34). Moreover, CPR with a chest compression performed accurately can merely provide 20% -30% of the systolic cardiac output (35). Chen et al pointed out that if the starting time of ECMO support is under 60 minutes in cardiac arrest, the survival rate of patients is higher (36).…”

Section: Discussionmentioning

confidence: 99%

Utilization of Extracorporeal Membrane Oxygenation In Pediatric Cardiac Surgery: A Single Center Experience, 34 Cases in 8 Years

Zeybek

Avsar

Yildirim³

et al. 2017

Iran J Pediatr

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Background: Extracorporeal membrane oxygenation (ECMO) is used in a variety of indications worldwide. One of the most important subsets is postoperative congenital cardiac surgery cases unresponsive to conventional therapies. In this study, we present our ECMO experience in a single congenital cardiac surgery center. Methods: ECMO was used in a total of 34 postoperative congenital cardiac surgery cases, whose operations had been performed by the same congenital cardiac surgery team. Patients' ages were between 3 days to 15 years. ECMO was used in four different indications; in case of unsuccessful weaning from cardiopulmonary bypass (OR-ECMO), in low cardiac output syndrome (LCOS-ECMO), in refractory post cardiac arrest (CPR-ECMO) and in respiratory insufficiency after RSV infection (RSV-ECMO). Results: The follow-up period of patients ranged from 1 to 80 months, whereas ECMO duration ranged from 23 to 2218 hours. Six cases were OR-ECMO, 13 were LCOS-ECMO, 12 were CPR-ECMO and 3 were RSV-ECMO. Out of a total of 34 cases, 20 (58%) cases were weaned from ECMO. Two of the patients, who were able to be weaned from ECMO passed away in the hospital; however, the other 18 patients (52.9%) were discharged from the hospital without having any significant neurological deficits. The top survival rate (69%) and weaning from ECMO was in the LCOS-ECMO group and the worst weaning from ECMO support (33%) was in the RSV-ECMO. The worst survival rate (25%) was in the CPR-ECMO group. Sepsis and associated multiple organ dysfunction were observed as the major cause of mortality in these patients. The most common complications were bleeding and mechanical complications related to cannulation. Conclusions: ECMO may be required in postoperative congenital cardiac surgery cases in whom all other conventional therapies have failed. Indications, timing and maintenance of equipment are very important points in successful ECMO management. Increasing ECMO experience in the near future, will provide much decrease in mortality of congenital cardiac surgery.

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Experimental design for study of cardiopulmonary resuscitation in dogs

Cited by 59 publications

References 12 publications

Clinical outcomes after rescue extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest

Clinical outcomes after rescue extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest

Estimation of anatomical structures underneath the chest compression landmarks in children by using computed tomography

Utilization of Extracorporeal Membrane Oxygenation In Pediatric Cardiac Surgery: A Single Center Experience, 34 Cases in 8 Years

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