In the paper, based on the results of the experimental research of high-strength low-alloy steel (HSLA), Nionicral 70 (NN-70), under conditions of low-cycle fatigue (LCF), a numerical analysis of stress and determination of the life of steel samples was performed. Experimental testing of the behavior of the samples were performed with controlled and fully reversible strain (/2 = const,
R = min/max = -1), according to the standard ISO 12106:2003 (E). For computational analyses, the following were used: the method of least squares and the method of finite elements (FEM). On the basis of the analysis of the results of the stress-deformation state and the determination of the life span through the isolines of the life span and comparison with the results of experimental tests, a graphic representation is given. The analysis justified the effort to numerically solve the estimation of the lifespan of steel under low cycle fatigue (LCF).