Experimental Determination of the Normalized Index of Hemolysis for the Sputnik Implantable Pediatric Rotary Blood Pump

Bockeriа, L.A.; Bockeria, O.L.; Селищев, С. В.; Telyshev, D. V.; Le, T. G.; Satyukova, A. S.; Shvartz, Vladimir A.; Glushko, L. A.

doi:10.1007/s10527-017-9668-9

Cited by 3 publications

(4 citation statements)

References 2 publications

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“…The blood pump is the core component responsible for generating blood circulation energy in VAD and its design directly affects the health of patients. 2,3 The working mechanism of the blood pump is similar to that of industrial water pumps and the circulating energy of the fluid is generated by the high-speed rotation of the impeller. However, the working medium of the blood pump is blood, so the design must ensure that it does not cause excessive damage to the blood.…”

Section: Introductionmentioning

confidence: 99%

“…The blood pump is the core component responsible for generating blood circulation energy in VAD and its design directly affects the health of patients. 2 , 3 …”

Section: Introductionmentioning

confidence: 99%

“…The blood damage caused by the blood pump is thought to be mainly caused by the shear stress in the flow field. 2 , 4 , 5 Because the impeller is the core structure that generates fluid energy and affects the flow field, the structural design of the impeller is directly related to the performance of the blood pump.…”

Section: Introductionmentioning

confidence: 99%

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Multiple parameters and target optimization of splitter blades for axial spiral blade blood pump using computational fluid mechanics, neural networks, and particle image velocimetry experiment

Tan

Wang

et al. 2021

Science Progress

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The blood pump is an implantable device with strict performance requirements. Any effective structural improvement will help to improve the treatment of patients. However, the research of blood pump structure improvement is a complex optimization problem with multiple parameters and objectives. This study takes the splitter blade as the object of structural improvement. Computational fluid mechanics and neural networks are combined in research and optimization. And hydraulic experiments and micro particle image velocimetry technology were used. In the optimization study, the number of blades, axial length and circumferential offset are optimization parameters, and hydraulic performance and hemolytic prediction index are optimization targets. The study analyzes the influence of each parameter on performance and completes the optimization of the parameters. In the results, the optimal parameters of number of blades, axial length ratio, and circumferential offset are 2.6° and 0.41°, respectively. Under optimized parameters, hydraulic performance can be significantly improved. And the results of hemolysis prediction and micro particle image velocimetry experiments reflect that there is no increase in the risk of hemolytic damage. The results of this study provide a method and ideas for improving the structure of the axial spiral blade blood pump. The established optimization method can be effectively applied to the design and research of axial spiral blade blood pumps with complex, high precision, and multiple parameters and targets.

show abstract

Section: Introductionmentioning

confidence: 99%

“…The blood pump is the core component responsible for generating blood circulation energy in VAD and its design directly affects the health of patients. 2 , 3 …”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Multiple parameters and target optimization of splitter blades for axial spiral blade blood pump using computational fluid mechanics, neural networks, and particle image velocimetry experiment

Tan

Wang

et al. 2021

Science Progress

View full text Add to dashboard Cite

show abstract

“…However, the working medium of the blood pump is blood, so the design must ensure that it does not cause 3 excessive damage to the blood. The blood damage caused by the blood pump is thought to be mainly caused by the shear stress in the flow field [2,4,5]. Because the impeller is the core structure that generates fluid energy and affects the flow field, the structural design of the impeller is directly related to the performance of the blood pump.…”

Section: Introductionmentioning

confidence: 99%

Multiple Parameters and Target Optimization of Splitter Blades for Blood Pumps Using CFD and Neural Networks

Yu¹,

Tan²,

Wang³

2020

Preprint

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Background: The splitter blade is an improved structure effective in traditional pumps. However, applying splitter blades to blood pumps is a complex optimization problem with multiple parameters and objectives, because structural parameters, blood circulation dynamics, and blood damage need to be considered simultaneously. This study aims to obtain the performance impact of the splitter blade and make it well used in blood pumps through CFD and neural networks.Results: This study combines CFD and neural networks. And hydraulic experiments and PIV technology were used. In the optimization study, the number of blades, axial length, and circumferential offset are optimization parameters, and hydraulic performance and hemolytic prediction index are optimization targets. The study analyzes the influence of each parameter on performance and completes the optimization of the parameters. In the results, the optimal parameters of the number of blades, axial length ratio, and circumferential offset are 2, 6 °, and 0.41, respectively. Under optimized parameters, hydraulic performance can be significantly improved. And the results of hemolysis prediction and micro PIV experiments reflect that there is no increase in the risk of hemolytic damage.Conclusion: This study provides a method and ideas for improving the structure of the blood pump. The established optimization method can be effectively applied to the design and research of blood pumps with complex, high precision, and multiple parameters and targets.

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A Mock Circulatory System for Testing Pediatric Rotary Blood Pumps

2017

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Experimental Determination of the Normalized Index of Hemolysis for the Sputnik Implantable Pediatric Rotary Blood Pump

Cited by 3 publications

References 2 publications

Multiple parameters and target optimization of splitter blades for axial spiral blade blood pump using computational fluid mechanics, neural networks, and particle image velocimetry experiment

Multiple parameters and target optimization of splitter blades for axial spiral blade blood pump using computational fluid mechanics, neural networks, and particle image velocimetry experiment

Multiple Parameters and Target Optimization of Splitter Blades for Blood Pumps Using CFD and Neural Networks

A Mock Circulatory System for Testing Pediatric Rotary Blood Pumps

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