Experimental evaluation of the antioxidant and antitumor activities of thyme and basil essential oils and their phenolic constituents: theoretical antioxidant evaluation

Ramadan, Khaled M. A.; El-Beltagi, Hossam S.; Bendary, Eslam S. A.; Ali, Hussein M.

doi:10.1186/s40538-022-00366-4

Cited by 7 publications

(8 citation statements)

References 46 publications

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“…Thyme plants and their essential oil components possess antibacterial, antiviral, and antioxidant properties. Therefore, they are widely used in the pharmaceutical, food, and cosmetic industries [85][86][87]. Revealing the composition and characteristics of the T. mongolicus genome is crucial for the development and utilization of its genetic resources.…”

Section: Discussionmentioning

confidence: 99%

Chromosome-level genome assembly provides insights into the genome evolution and functional importance of the phenylpropanoid–flavonoid pathway in Thymus mongolicus

Dang,

Xu,

Zhang

et al. 2024

BMC Genomics

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Background Thymus mongolicus (family Lamiaceae) is a Thyme subshrub with strong aroma and remarkable environmental adaptability. Limited genomic information limits the use of this plant. Results Chromosome-level 605.2 Mb genome of T. mongolicus was generated, with 96.28% anchored to 12 pseudochromosomes. The repetitive sequences were dominant, accounting for 70.98%, and 32,593 protein-coding genes were predicted. Synteny analysis revealed that Lamiaceae species generally underwent two rounds of whole genome duplication; moreover, species-specific genome duplication was identified. A recent LTR retrotransposon burst and tandem duplication might play important roles in the formation of the Thymus genome. Using comparative genomic analysis, phylogenetic tree of seven Lamiaceae species was constructed, which revealed that Thyme plants evolved recently in the family. Under the phylogenetic framework, we performed functional enrichment analysis of the genes on nodes that contained the most gene duplication events (> 50% support) and of relevant significant expanded gene families. These genes were highly associated with environmental adaptation and biosynthesis of secondary metabolites. Combined transcriptome and metabolome analyses revealed that Peroxidases, Hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyl transferases, and 4-coumarate-CoA ligases genes were the essential regulators of the phenylpropanoid–flavonoid pathway. Their catalytic products (e.g., apigenin, naringenin chalcone, and several apigenin-related compounds) might be responsible for the environmental tolerance and aromatic properties of T. mongolicus. Conclusion This study enhanced the understanding of the genomic evolution of T. mongolicus, enabling further exploration of its unique traits and applications, and contributed to the understanding of Lamiaceae genomics and evolutionary biology.

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Section: Discussionmentioning

confidence: 99%

Chromosome-level genome assembly provides insights into the genome evolution and functional importance of the phenylpropanoid–flavonoid pathway in Thymus mongolicus

Dang,

Xu,

Zhang

et al. 2024

BMC Genomics

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“…Determining the biological and antioxidant activities of natural products is a major concern worldwide for their use in the manufacture of safe functional foods. EOs and the plant organs they contain are good candidates in this regard [92]. The higher scavenging activity of fruit extracts of fertilized fennel may be due to the increased content of phenols and flavonoid phytomolecules.…”

Section: Discussionmentioning

confidence: 99%

Effect of Organic and Bio-Fertilization on Fruit Yield, Bioactive Constituents, and Estragole Content in Fennel Fruits

et al. 2023

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Fennel fruits (Foeniculum vulgare Mill.) represent one of the plant-based natural spices. This study aims to improve the fruit yield and essential oil (EO) quality by reducing the undesirable component, estragole, under different fertilizer treatments. The fertilizers included chemical nitrogen, phosphorus, and potassium (NPK), and also the organic additive, rabbit manure (RM). For bio-fertilization, plants were inoculated with a mixture of N-fixing bacteria, and P- and K-solubilizing bacteria with/without vesicular-arbuscular mycorrhizal fungi. The results showed that fruit and EO yield parameters, total phenolic content (TPC), total flavonoid content (TFC), and DPPH scavenging activity of fruit extracts were enhanced by fertilizer treatments in both growing seasons. NPK at 150% of the recommended dose (NPK150) and RM at 60 m3/fed (RM60) recorded the highest values of plant height, umbel number/plant, 100-fruit weight, fruit yield, chlorophyll, carbohydrates, N and P content, EO content, and yield. TPC and TFC were enhanced by using biological fertilizers. DPPH scavenging activity was higher in organically and biologically fertilized fennel. The GC-MS analyses of EO revealed higher contents of the desirable trans-anethole in the organically and chemically fertilized fennel. However, the highest proportion of estragole, the undesirable compound, was recorded for NPK150 and unfertilized plants. On the contrary, increases in the EO content and yield of fennel fruits were achieved by RM along with a reduction in estragole, enhancement in trans-anethole, and increments in other favorable compounds such as fenchone and limonene. In addition, the inhibition of estragole formation was recorded with bio-fertilizers, which also increased the trans-anethole content. Furthermore, the trans-anethole/estragole ratio was significantly higher with the application of organic and bio-fertilization. Hence, organic and bio-fertilizer resources can produce high-quality fennel fruit and EO. The reduction in the use of chemical fertilizers can help to reduce environmental pollution.

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“…The CDs and CTs were significantly (P<0.01) reduced to 5.2 and 4.4 in corn oil when beta-carotene was used at 20 µg/mL and 5.8 and 5.1 for curcumin at 120 µg/mL. Changes in the concentration of CDs were an effective indicator for tracking lipid oxidation under accelerated oxidation settings against corn oil in the presence or absence of natural antioxidant extract or synthetic antioxidants [37][38][39]. A possible link between CDs synthesis and the abundance of polyunsaturated fatty acids in modern cooking oils has been suggested [16].…”

Section: Changes In Conjugated Dienes and Conjugated Trienesmentioning

confidence: 92%

Improving Oxidative Stability of Corn Oil by Curcumin and Beta-Carotene under Accelerated Oxidation Conditions

El-Beltag,

Hussein,

E.A.A

et al. 2023

Pol. J. Environ. Stud.

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Vegetable oils, such as corn oil, are highly recommended as a human cooking medium due to their high polyunsaturated fatty acid content and their many healthful impacts on the human body [1,2]. Fried foods are well-liked across the world because of their distinctive flavor and texture. Takeouts and fast food, which are more popular than ever, both make use of frying and deep frying techniques on a regular basis [3]. When subjected to harsh environmental variables such as constant high temperature, air, and light, the chemical structure of fatty acids and their derivatives (triglycerides) become unstable. Due to their highfat content, fatty acids and their derivatives are easily oxidized by chemicals, a process that leaves a rancid taste and reduces their shelf life [4]. When oils are improperly stored (chemically or ecologically), oxidation

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Experimental evaluation of the antioxidant and antitumor activities of thyme and basil essential oils and their phenolic constituents: theoretical antioxidant evaluation

Cited by 7 publications

References 46 publications

Chromosome-level genome assembly provides insights into the genome evolution and functional importance of the phenylpropanoid–flavonoid pathway in Thymus mongolicus

Chromosome-level genome assembly provides insights into the genome evolution and functional importance of the phenylpropanoid–flavonoid pathway in Thymus mongolicus

Effect of Organic and Bio-Fertilization on Fruit Yield, Bioactive Constituents, and Estragole Content in Fennel Fruits

Improving Oxidative Stability of Corn Oil by Curcumin and Beta-Carotene under Accelerated Oxidation Conditions

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