Experimental evaluation of the injection force exerted in intraocular lens delivery with syringe-type injectors

Cabeza-Gil, Iulen; Ríos-Ruiz, Itziar; Calvo, Begoña

doi:10.1016/j.jmbbm.2021.104793

Cited by 11 publications

(7 citation statements)

References 26 publications

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“…Ejection tests are carried out in vitro, measuring the resistance force throughout the entire delivery process. The effect of IOL material, haptic design, IOL thickest area, and ophthalmic viscosurgical device (OVD) have been studied by ejecting several IOLs with syringe-type injectors of different sizes, 3.0, 2.2, and 1.8 mm [ 55 ]. It has been observed that plate hydrophilic IOLs present the lowest resistance forces; hydrated C-loop hydrophobic IOLs present higher forces and the C-loop hydrophobic IOL in dry conditions presents the highest resistance forces.…”

Section: Iols Materials Marketmentioning

confidence: 99%

Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power

et al. 2023

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Intraocular lenses (IOLs) are commonly implanted after surgical removal of a cataractous lens. A variety of IOL materials are currently available, including collamer, hydrophobic acrylic, hydrophilic acrylic, PHEMA copolymer, polymethylmethacrylate (PMMA), and silicone. High-quality polymers with distinct physical and optical properties for IOL manufacturing and in line with the highest quality standards on the market have evolved to encompass medical needs. Each of them and their packaging show unique advantages and disadvantages. Here, we highlight the evolution of polymeric materials and mainly the current state of the art of the unique properties of some polymeric systems used for IOL design, identifying current limitations for future improvements. We investigate the characteristics of the next generation of IOL materials, which must satisfy biocompatibility requirements and have tuneable refractive index to create patient-specific eye power, preventing formation of posterior capsular opacification.

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Section: Iols Materials Marketmentioning

confidence: 99%

Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power

et al. 2023

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“…[18] According to international organization for standardization (ISO), syringe performance can be measured by the value of its dead space, force operation, leakage, and plunger position in the barrel. [19] Previous studies indicate that the dimension and shape of the syringe affect the dead space, [20][21][22][23][24][25][26][27][28][29] force operation, [8,22,[30][31][32][33] and leakage. [34][35][36] Besides the performance, the shape and dimension of a syringe also affect user perception of safe products [37][38][39][40][41] and product features.…”

Section: Introductionmentioning

confidence: 99%

An analysis of the effect of syringe barrel volume on performance and user perception

et al. 2023

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In the market, there are many types and shapes of syringes. One of the groupings of syringe types is based on barrel volume. The shape of the product design affects performance and user perception. The aim of this study is to investigate the effect of barrel volume on its performance and user perception. We performed analysis following international organization for standardization 7886 procedures on syringe with 1 mL, 3 mL, 5 mL, and 10 mL volume. In addition, a user perception test was conducted on 29 respondents using a questionnaire with the Likert chart method. This study indicates that the bigger the syringe volume, the larger the dead space and the force to operate the piston are. A larger syringe volume also raises the volume that changes due to the plunger position increase. Meanwhile, the barrel volume does not affect water and water leakage, as we did not observe any leak during the syringe tests in our experiment. In addition, the user perception test shows that the barrel’s length influences the ease of device control during the injection. The volume of the barrel negatively correlated with its effect to the environment. The safety features of all syringes are similar except for the 3 mL syringe, which has a value of 0.1 points difference to other syringes.

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“…Based on the security standards that have been regulated in ISO, several performance tests have been regulated, the syringe performance test consists of dead space, freedom from leakage, operating piston force, and fit of the plunger in the barrel. [24] Syringe type affects the dead space, [2,6,[35][36][37][38][39][40][41][42] , operating force [23,39,[43][44][45][46] , and leakage [47][48][49] . In addition to dead space testing, freedom from air and liquid leaked past the plunger stopper, forced the piston to operate, and fit the plunger stopper/plunger in the barrel, which are of concern in the use of syringes such as those carried out by Struik et al They compared the performance of a single-use Figure 1.…”

Section: Introductionmentioning

confidence: 99%

The hypodermic syringe performance based on the ISO 7886-1:2017: A narrative review

et al. 2022

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A syringe is used to inject fluid or medicine into the patient's soft tissue. The main components of the syringe were the needle, barrel, and plunger. The use of syringes in the medical world is relatively high, and especially since the COVID-19 pandemic, the use of hypodermic syringes increased sharply due to vaccination. The syringe used must be effective and of good quality, so the International Organization for Standardization (ISO) has published test procedures and minimum specifications for hypodermic syringes. The performance of the syringe can be observed from the dead space, force piston operation, water and air leakage, and fitting position of the plunger in the barrel. This review shows that most researchers use the weighing method to measure the dead space, although some use other methods. The researchers found that most of the products met the minimum specifications of the ISO, and that the dimensions and shape of the syringe affected the dead space. Researchers have not examined other performance measures recommended by the ISO. Researchers have focused more on force injection than force piston operation, leakage after injection or back spray than air and water leakage, and reduction the friction of the plunger without considering the fitting position of the plunger in the barrel.

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Experimental evaluation of the injection force exerted in intraocular lens delivery with syringe-type injectors

Cited by 11 publications

References 26 publications

Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power

Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power

An analysis of the effect of syringe barrel volume on performance and user perception

The hypodermic syringe performance based on the ISO 7886-1:2017: A narrative review

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